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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIP2A All Species: 25.76
Human Site: T176 Identified Species: 56.67
UniProt: Q14689 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14689 NP_001139586.1 1571 170369 T176 R V I Q G S S T S S S A S S T
Chimpanzee Pan troglodytes XP_514951 1741 187434 T346 R V I Q G S S T S S S A S S T
Rhesus Macaque Macaca mulatta XP_001082991 1573 170832 T184 R S I Q G S S T S S S A S S T
Dog Lupus familis XP_548736 1617 176089 T228 R V I Q G S S T S S S A S S T
Cat Felis silvestris
Mouse Mus musculus Q8BWT5 1523 165255 L164 A S T A L A G L T A H A H I D
Rat Rattus norvegicus XP_001070526 1561 169349 T174 R V I Q G S S T S S S A S S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509877 1556 170889 S174 A I H G S T T S T T S S S S T
Chicken Gallus gallus XP_001234676 1571 171251 T178 R V I Q G S S T S S S A S S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NVJ5 1577 171660 Q174 Y W I N R S V Q G S S T S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0S9 1773 194136 R170 N S Q H R Q R R T Q R K V T H
Honey Bee Apis mellifera XP_391894 1679 181987 G258 L S D T S S T G S A R D T P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 70.3 90.4 N.A. 91.4 92.8 N.A. 74.8 89.4 N.A. 71.4 N.A. 50.8 56.9 N.A. N.A.
Protein Similarity: 100 90.1 83.1 93.3 N.A. 93.8 95.6 N.A. 86.3 93.9 N.A. 83.6 N.A. 64.4 70.6 N.A. N.A.
P-Site Identity: 100 100 93.3 100 N.A. 6.6 100 N.A. 26.6 100 N.A. 40 N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 26.6 100 N.A. 73.3 100 N.A. 46.6 N.A. 13.3 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 10 0 10 0 0 0 19 0 64 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 55 0 10 10 10 0 0 0 0 0 0 % G
% His: 0 0 10 10 0 0 0 0 0 0 10 0 10 0 10 % H
% Ile: 0 10 64 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 10 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % P
% Gln: 0 0 10 55 0 10 0 10 0 10 0 0 0 0 0 % Q
% Arg: 55 0 0 0 19 0 10 10 0 0 19 0 0 0 0 % R
% Ser: 0 37 0 0 19 73 55 10 64 64 73 10 73 73 10 % S
% Thr: 0 0 10 10 0 10 19 55 28 10 0 10 10 10 64 % T
% Val: 0 46 0 0 0 0 10 0 0 0 0 0 10 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _