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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS1 All Species: 33.03
Human Site: S173 Identified Species: 60.56
UniProt: Q14691 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14691 NP_066545.3 196 22988 S173 S V L L K K N S Q H F L P R W
Chimpanzee Pan troglodytes XP_001150442 157 18389 K142 Q H F L P R W K C E Q L I R Q
Rhesus Macaque Macaca mulatta XP_001107106 260 30566 S237 S V L L K K N S Q H F L P R W
Dog Lupus familis XP_848652 196 22905 S173 S V L L K K N S Q H F L P R W
Cat Felis silvestris
Mouse Mus musculus Q9CZ15 196 22875 S173 S V L L K K N S Q H F L P R W
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519883 136 15929 L122 D D G T S I L L K K N S Q V F
Chicken Gallus gallus NP_001012621 195 22763 S172 T V L L K K N S Q H F L P R W
Frog Xenopus laevis NP_001085502 196 23120 S173 T I L L K K N S Q H F L P R W
Zebra Danio Brachydanio rerio NP_001006081 196 23050 S173 V I L L K K N S Q H F L P R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395538 194 22509 T171 V I L L K K N T Y H L L P R S
Nematode Worm Caenorhab. elegans Q22019 201 22718 S179 Q V Q L S K D S L H S L P R Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12488 208 24185 Q188 F N L I K D S Q F F V R Q S D
Red Bread Mold Neurospora crassa Q7SDH9 216 24135 Q195 I N L T K N S Q F Y V R Q G D
Conservation
Percent
Protein Identity: 100 80 74.2 95.4 N.A. 93.3 N.A. N.A. 62.7 77 88.7 84.1 N.A. N.A. 44.9 38.8 N.A.
Protein Similarity: 100 80 75.3 98.9 N.A. 98.4 N.A. N.A. 66.8 89.2 96.4 93.8 N.A. N.A. 68.8 62.6 N.A.
P-Site Identity: 100 20 100 100 N.A. 100 N.A. N.A. 0 93.3 86.6 86.6 N.A. N.A. 60 53.3 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 N.A. N.A. 13.3 100 100 93.3 N.A. N.A. 73.3 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.4 26.8
Protein Similarity: N.A. N.A. N.A. N.A. 50 46.7
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 8 8 0 0 0 0 0 0 0 16 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 8 0 8 0 0 0 0 0 16 8 54 0 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 8 0 0 0 0 0 0 0 70 0 0 0 0 0 % H
% Ile: 8 24 0 8 0 8 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 0 77 70 0 8 8 8 0 0 0 0 0 % K
% Leu: 0 0 77 77 0 0 8 8 8 0 8 77 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 0 0 0 8 62 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 70 0 0 % P
% Gln: 16 0 8 0 0 0 0 16 54 0 8 0 24 0 16 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 16 0 77 0 % R
% Ser: 31 0 0 0 16 0 16 62 0 0 8 8 0 8 8 % S
% Thr: 16 0 0 16 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 16 47 0 0 0 0 0 0 0 0 16 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 54 % W
% Tyr: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _