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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS1 All Species: 21.21
Human Site: S52 Identified Species: 38.89
UniProt: Q14691 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14691 NP_066545.3 196 22988 S52 S D V N E A K S G G R S D L I
Chimpanzee Pan troglodytes XP_001150442 157 18389 E26 G Q L P A F N E D G L R Q V L
Rhesus Macaque Macaca mulatta XP_001107106 260 30566 S116 S D V N E A K S G G R S D L I
Dog Lupus familis XP_848652 196 22905 S52 S D V N E V K S G G R S D L I
Cat Felis silvestris
Mouse Mus musculus Q9CZ15 196 22875 S52 S D V N E A K S A G R G D L I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519883 136 15929
Chicken Gallus gallus NP_001012621 195 22763 K51 Q A D V S E A K S G R T D L I
Frog Xenopus laevis NP_001085502 196 23120 T52 A D V N E A K T E G R S D L I
Zebra Danio Brachydanio rerio NP_001006081 196 23050 T52 T D V N E A K T E G K S E L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395538 194 22509 N50 A D S N A I R N D D N M A L L
Nematode Worm Caenorhab. elegans Q22019 201 22718 R59 A A V V E K I R A G L P H D S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12488 208 24185 L60 Y L K E Q Q Q L G M L D D K V
Red Bread Mold Neurospora crassa Q7SDH9 216 24135 P59 P F Q G S F D P S A E Q A T A
Conservation
Percent
Protein Identity: 100 80 74.2 95.4 N.A. 93.3 N.A. N.A. 62.7 77 88.7 84.1 N.A. N.A. 44.9 38.8 N.A.
Protein Similarity: 100 80 75.3 98.9 N.A. 98.4 N.A. N.A. 66.8 89.2 96.4 93.8 N.A. N.A. 68.8 62.6 N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 86.6 N.A. N.A. 0 33.3 80 66.6 N.A. N.A. 20 20 N.A.
P-Site Similarity: 100 26.6 100 93.3 N.A. 86.6 N.A. N.A. 0 40 93.3 93.3 N.A. N.A. 46.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.4 26.8
Protein Similarity: N.A. N.A. N.A. N.A. 50 46.7
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 16 0 0 16 39 8 0 16 8 0 0 16 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 54 8 0 0 0 8 0 16 8 0 8 54 8 0 % D
% Glu: 0 0 0 8 54 8 0 8 16 0 8 0 8 0 0 % E
% Phe: 0 8 0 0 0 16 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 0 0 0 0 31 70 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 54 % I
% Lys: 0 0 8 0 0 8 47 8 0 0 8 0 0 8 0 % K
% Leu: 0 8 8 0 0 0 0 8 0 0 24 0 0 62 16 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % M
% Asn: 0 0 0 54 0 0 8 8 0 0 8 0 0 0 0 % N
% Pro: 8 0 0 8 0 0 0 8 0 0 0 8 0 0 0 % P
% Gln: 8 8 8 0 8 8 8 0 0 0 0 8 8 0 0 % Q
% Arg: 0 0 0 0 0 0 8 8 0 0 47 8 0 0 0 % R
% Ser: 31 0 8 0 16 0 0 31 16 0 0 39 0 0 8 % S
% Thr: 8 0 0 0 0 0 0 16 0 0 0 8 0 8 0 % T
% Val: 0 0 54 16 0 8 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _