Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS1 All Species: 29.39
Human Site: S96 Identified Species: 53.89
UniProt: Q14691 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14691 NP_066545.3 196 22988 S96 A L R W E Y G S V L P N A L R
Chimpanzee Pan troglodytes XP_001150442 157 18389 L70 K F R H C S L L R N R R C T V
Rhesus Macaque Macaca mulatta XP_001107106 260 30566 S160 A L R W E Y G S I L P N A L R
Dog Lupus familis XP_848652 196 22905 S96 A L R W E Y G S V L P N A L R
Cat Felis silvestris
Mouse Mus musculus Q9CZ15 196 22875 S96 A L R W E Y G S V L P N S L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519883 136 15929 L51 R W E Y G S I L P N T L R F H
Chicken Gallus gallus NP_001012621 195 22763 S95 A L R W E Y G S I L P N T I Q
Frog Xenopus laevis NP_001085502 196 23120 S96 A L R W E Y G S V L P S A L R
Zebra Danio Brachydanio rerio NP_001006081 196 23050 S96 A L R W E Y G S V L P T N I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395538 194 22509 S94 E L R W E L G S I L P P E I N
Nematode Worm Caenorhab. elegans Q22019 201 22718 G103 S F R W K Y G G A L P A S V R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12488 208 24185 N104 L D S M A W N N N G L D L M S
Red Bread Mold Neurospora crassa Q7SDH9 216 24135 D103 E L V W N G A D I L D L A G Q
Conservation
Percent
Protein Identity: 100 80 74.2 95.4 N.A. 93.3 N.A. N.A. 62.7 77 88.7 84.1 N.A. N.A. 44.9 38.8 N.A.
Protein Similarity: 100 80 75.3 98.9 N.A. 98.4 N.A. N.A. 66.8 89.2 96.4 93.8 N.A. N.A. 68.8 62.6 N.A.
P-Site Identity: 100 6.6 93.3 100 N.A. 93.3 N.A. N.A. 0 73.3 93.3 80 N.A. N.A. 53.3 46.6 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 N.A. N.A. 6.6 93.3 100 86.6 N.A. N.A. 66.6 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.4 26.8
Protein Similarity: N.A. N.A. N.A. N.A. 50 46.7
P-Site Identity: N.A. N.A. N.A. N.A. 0 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 54 0 0 0 8 0 8 0 8 0 0 8 39 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 8 0 0 0 0 0 8 0 0 8 8 0 0 0 % D
% Glu: 16 0 8 0 62 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 16 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 8 8 70 8 0 8 0 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 8 0 31 0 0 0 0 24 0 % I
% Lys: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 70 0 0 0 8 8 16 0 77 8 16 8 39 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 8 0 8 8 8 16 0 39 8 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 70 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % Q
% Arg: 8 0 77 0 0 0 0 0 8 0 8 8 8 0 54 % R
% Ser: 8 0 8 0 0 16 0 62 0 0 0 8 16 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 8 8 8 8 0 % T
% Val: 0 0 8 0 0 0 0 0 39 0 0 0 0 8 8 % V
% Trp: 0 8 0 77 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 62 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _