Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS1 All Species: 35.15
Human Site: T137 Identified Species: 64.44
UniProt: Q14691 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14691 NP_066545.3 196 22988 T137 G D E G L D I T Q D M K P P K
Chimpanzee Pan troglodytes XP_001150442 157 18389 M106 P N A L R F H M A A E E V R C
Rhesus Macaque Macaca mulatta XP_001107106 260 30566 T201 G D E G L D I T Q D V K P P K
Dog Lupus familis XP_848652 196 22905 T137 G D E G L D I T Q D M K P P K
Cat Felis silvestris
Mouse Mus musculus Q9CZ15 196 22875 T137 G D E G L D I T Q D V K P P K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519883 136 15929 G86 R S L G G D E G L D I T Q D I
Chicken Gallus gallus NP_001012621 195 22763 T136 G E E G L D L T Q D I K P P K
Frog Xenopus laevis NP_001085502 196 23120 T137 G E E G L D I T Q D M K P P K
Zebra Danio Brachydanio rerio NP_001006081 196 23050 T137 G E E G L D I T Q D M K P P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395538 194 22509 T135 E D Y G F N L T T N I L P P K
Nematode Worm Caenorhab. elegans Q22019 201 22718 L143 G E G G V N L L L H S A P P K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12488 208 24185 S152 D L V D I D L S G S L V P P S
Red Bread Mold Neurospora crassa Q7SDH9 216 24135 T159 Q W T D I D L T G S L E P P R
Conservation
Percent
Protein Identity: 100 80 74.2 95.4 N.A. 93.3 N.A. N.A. 62.7 77 88.7 84.1 N.A. N.A. 44.9 38.8 N.A.
Protein Similarity: 100 80 75.3 98.9 N.A. 98.4 N.A. N.A. 66.8 89.2 96.4 93.8 N.A. N.A. 68.8 62.6 N.A.
P-Site Identity: 100 0 93.3 100 N.A. 93.3 N.A. N.A. 20 80 93.3 93.3 N.A. N.A. 40 33.3 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 N.A. N.A. 26.6 100 100 100 N.A. N.A. 66.6 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.4 26.8
Protein Similarity: N.A. N.A. N.A. N.A. 50 46.7
P-Site Identity: N.A. N.A. N.A. N.A. 20 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 8 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 8 39 0 16 0 77 0 0 0 62 0 0 0 8 0 % D
% Glu: 8 31 54 0 0 0 8 0 0 0 8 16 0 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 62 0 8 77 8 0 0 8 16 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 16 0 47 0 0 0 24 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 54 0 0 70 % K
% Leu: 0 8 8 8 54 0 39 8 16 0 16 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 31 0 0 0 0 % M
% Asn: 0 8 0 0 0 16 0 0 0 8 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 85 85 0 % P
% Gln: 8 0 0 0 0 0 0 0 54 0 0 0 8 0 0 % Q
% Arg: 8 0 0 0 8 0 0 0 0 0 0 0 0 8 8 % R
% Ser: 0 8 0 0 0 0 0 8 0 16 8 0 0 0 8 % S
% Thr: 0 0 8 0 0 0 0 70 8 0 0 8 0 0 0 % T
% Val: 0 0 8 0 8 0 0 0 0 0 16 8 8 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _