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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS1 All Species: 31.21
Human Site: T165 Identified Species: 57.22
UniProt: Q14691 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14691 NP_066545.3 196 22988 T165 E F E V D D G T S V L L K K N
Chimpanzee Pan troglodytes XP_001150442 157 18389 S134 S V L L K K N S Q H F L P R W
Rhesus Macaque Macaca mulatta XP_001107106 260 30566 T229 E F E V D D G T S V L L K K N
Dog Lupus familis XP_848652 196 22905 T165 E F E V D D G T S V L L K K N
Cat Felis silvestris
Mouse Mus musculus Q9CZ15 196 22875 T165 E F E V D D G T S V L L K K N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519883 136 15929 I114 K D Y G E F E I D D G T S I L
Chicken Gallus gallus NP_001012621 195 22763 T164 E F E I D D G T T V L L K K N
Frog Xenopus laevis NP_001085502 196 23120 T165 E F E I D D G T T I L L K K N
Zebra Danio Brachydanio rerio NP_001006081 196 23050 T165 E F E I D D G T V I L L K K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395538 194 22509 Q163 R L E L E D G Q V I L L K K N
Nematode Worm Caenorhab. elegans Q22019 201 22718 T171 E F E T S D G T Q V Q L S K D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12488 208 24185 V180 E I Q T E Y G V F N L I K D S
Red Bread Mold Neurospora crassa Q7SDH9 216 24135 A187 E I Q T E Y G A I N L T K N S
Conservation
Percent
Protein Identity: 100 80 74.2 95.4 N.A. 93.3 N.A. N.A. 62.7 77 88.7 84.1 N.A. N.A. 44.9 38.8 N.A.
Protein Similarity: 100 80 75.3 98.9 N.A. 98.4 N.A. N.A. 66.8 89.2 96.4 93.8 N.A. N.A. 68.8 62.6 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 N.A. N.A. 0 86.6 80 80 N.A. N.A. 53.3 60 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 N.A. N.A. 13.3 100 100 93.3 N.A. N.A. 73.3 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.4 26.8
Protein Similarity: N.A. N.A. N.A. N.A. 50 46.7
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 54 70 0 0 8 8 0 0 0 8 8 % D
% Glu: 77 0 70 0 31 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 62 0 0 0 8 0 0 8 0 8 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 85 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 16 0 24 0 0 0 8 8 24 0 8 0 8 0 % I
% Lys: 8 0 0 0 8 8 0 0 0 0 0 0 77 70 0 % K
% Leu: 0 8 8 16 0 0 0 0 0 0 77 77 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 16 0 0 0 8 62 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 16 0 0 0 0 8 16 0 8 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 0 0 0 8 0 0 8 31 0 0 0 16 0 16 % S
% Thr: 0 0 0 24 0 0 0 62 16 0 0 16 0 0 0 % T
% Val: 0 8 0 31 0 0 0 8 16 47 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 8 0 0 16 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _