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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GINS1
All Species:
30
Human Site:
Y117
Identified Species:
55
UniProt:
Q14691
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14691
NP_066545.3
196
22988
Y117
E
M
E
W
F
N
N
Y
K
R
S
L
A
T
Y
Chimpanzee
Pan troglodytes
XP_001150442
157
18389
R86
Y
L
Y
D
R
L
L
R
I
R
A
L
R
W
E
Rhesus Macaque
Macaca mulatta
XP_001107106
260
30566
Y181
E
M
E
W
F
N
N
Y
K
R
S
L
A
T
Y
Dog
Lupus familis
XP_848652
196
22905
Y117
E
V
E
W
F
N
H
Y
K
K
S
L
A
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ15
196
22875
Y117
E
T
E
W
F
N
H
Y
K
K
S
L
A
T
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519883
136
15929
W66
M
S
A
E
E
M
Q
W
F
N
Q
Y
K
K
S
Chicken
Gallus gallus
NP_001012621
195
22763
Y116
E
V
E
W
F
N
R
Y
K
K
S
L
A
T
Y
Frog
Xenopus laevis
NP_001085502
196
23120
Y117
E
M
D
W
F
N
Q
Y
K
R
S
L
A
T
Y
Zebra Danio
Brachydanio rerio
NP_001006081
196
23050
Y117
E
M
E
W
F
N
Q
Y
K
K
S
L
A
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395538
194
22509
Y115
E
I
Q
W
F
Q
S
Y
N
K
S
L
A
T
Y
Nematode Worm
Caenorhab. elegans
Q22019
201
22718
E123
A
E
I
Q
F
F
N
E
Y
S
S
T
L
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12488
208
24185
K132
H
Q
E
Q
E
Y
L
K
E
Y
C
D
L
I
T
Red Bread Mold
Neurospora crassa
Q7SDH9
216
24135
F139
S
P
Q
E
E
D
Y
F
R
Q
F
G
D
L
L
Conservation
Percent
Protein Identity:
100
80
74.2
95.4
N.A.
93.3
N.A.
N.A.
62.7
77
88.7
84.1
N.A.
N.A.
44.9
38.8
N.A.
Protein Similarity:
100
80
75.3
98.9
N.A.
98.4
N.A.
N.A.
66.8
89.2
96.4
93.8
N.A.
N.A.
68.8
62.6
N.A.
P-Site Identity:
100
13.3
100
80
N.A.
80
N.A.
N.A.
0
80
86.6
86.6
N.A.
N.A.
60
20
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
N.A.
N.A.
6.6
93.3
93.3
93.3
N.A.
N.A.
86.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
26.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
46.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
0
8
0
62
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
0
0
0
0
0
8
8
0
0
% D
% Glu:
62
8
54
16
24
0
0
8
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
70
8
0
8
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
8
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
54
39
0
0
8
8
0
% K
% Leu:
0
8
0
0
0
8
16
0
0
0
0
70
16
8
8
% L
% Met:
8
31
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
54
24
0
8
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
16
16
0
8
24
0
0
8
8
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
8
8
8
31
0
0
8
0
8
% R
% Ser:
8
8
0
0
0
0
8
0
0
8
70
0
0
0
8
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
0
62
8
% T
% Val:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
62
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
8
0
8
0
0
8
8
62
8
8
0
8
0
0
62
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _