Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP10 All Species: 20
Human Site: S349 Identified Species: 36.67
UniProt: Q14694 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14694 NP_005144.2 798 87134 S349 W A S L F H D S K P S S S S P
Chimpanzee Pan troglodytes XP_511147 902 98075 S475 W A S L F H D S K P S S S S P
Rhesus Macaque Macaca mulatta XP_001111197 930 101558 S481 W A S L F H D S K P S S S S P
Dog Lupus familis XP_536761 834 90976 S385 W A S L F H D S K P S S S S P
Cat Felis silvestris
Mouse Mus musculus P52479 792 87004 S346 L F H D S K P S A S S P M A Y
Rat Rattus norvegicus Q3KR59 794 87293 K346 A S L F H D S K P S S S S P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510486 793 87073 E355 S T P V A Y V E T K Y T P P P
Chicken Gallus gallus Q5ZJN4 785 86537 T348 T S V V Y V E T K Y T P P A T
Frog Xenopus laevis Q2NL57 791 87545 T347 H N S K P S S T P Q V A Y V E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122220 379 42828
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794239 817 88996 A351 P S A T P P A A K S W A S L F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FPS3 551 60422 G127 S N K S L N N G V A V K T D P
Baker's Yeast Sacchar. cerevisiae Q01477 912 101898 T394 S T N M A A A T I G K S S S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 84.4 85.4 N.A. 83.3 84.2 N.A. 79.6 78.5 70.5 N.A. N.A. N.A. 24.4 N.A. 36.6
Protein Similarity: 100 85.6 85.1 89 N.A. 88.8 88.7 N.A. 86.9 84.3 79.3 N.A. N.A. N.A. 35.5 N.A. 52.8
P-Site Identity: 100 100 100 100 N.A. 13.3 20 N.A. 6.6 6.6 6.6 N.A. N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 20 26.6 N.A. 26.6 53.3 20 N.A. N.A. N.A. 0 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 25.5 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 40.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 31 8 0 16 8 16 8 8 8 0 16 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 31 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 8 % E
% Phe: 0 8 0 8 31 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % G
% His: 8 0 8 0 8 31 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 8 8 0 8 0 8 47 8 8 8 0 0 0 % K
% Leu: 8 0 8 31 8 0 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 16 8 0 0 8 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 8 0 16 8 8 0 16 31 0 16 16 16 54 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 24 24 39 8 8 8 16 39 0 24 47 47 54 39 0 % S
% Thr: 8 16 0 8 0 0 0 24 8 0 8 8 8 0 8 % T
% Val: 0 0 8 16 0 8 8 0 8 0 16 0 0 8 8 % V
% Trp: 31 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 8 8 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _