KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MESDC2
All Species:
12.42
Human Site:
T125
Identified Species:
21.03
UniProt:
Q14696
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14696
NP_055969.1
234
26077
T125
V
T
V
S
G
S
P
T
E
K
E
T
E
E
I
Chimpanzee
Pan troglodytes
XP_001161202
85
9478
Rhesus Macaque
Macaca mulatta
XP_001109767
149
16578
R49
D
K
S
T
P
P
P
R
K
K
K
K
D
I
R
Dog
Lupus familis
XP_545883
190
21252
Q90
E
E
I
T
S
L
W
Q
G
S
L
F
N
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERE7
224
25188
T116
V
T
V
S
G
N
P
T
E
K
E
T
E
E
I
Rat
Rattus norvegicus
Q5U2R7
224
25197
T116
V
T
I
S
G
N
P
T
E
K
E
T
E
E
I
Wallaby
Macropus eugenll
Q9XT48
201
21518
S101
N
S
L
L
V
P
T
S
G
L
Y
F
V
Y
S
Platypus
Ornith. anatinus
XP_001514817
161
18036
I61
T
E
K
E
T
E
E
I
T
S
L
W
Q
G
S
Chicken
Gallus gallus
Q5ZKK4
220
24673
K111
V
S
G
N
P
T
E
K
E
T
E
E
I
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L243
206
23288
E106
S
V
S
G
N
P
T
E
K
E
T
E
E
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T9B6
180
20983
S80
L
S
N
L
D
S
K
S
P
E
D
L
L
K
V
Honey Bee
Apis mellifera
XP_001122588
178
21016
D78
K
I
D
I
S
K
L
D
M
S
N
P
D
N
V
Nematode Worm
Caenorhab. elegans
NP_495003
186
21786
K86
D
L
L
M
M
S
K
K
G
Q
T
L
M
L
F
Sea Urchin
Strong. purpuratus
XP_001188878
182
21140
W82
A
E
T
I
T
Q
R
W
Q
D
Q
L
F
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.9
61.1
67.5
N.A.
83.7
81.6
21.3
59.4
74.3
N.A.
64
N.A.
38.8
30.3
34.6
38.4
Protein Similarity:
100
36.3
62.8
73.5
N.A.
90.5
88.8
35.4
64
80.3
N.A.
73.9
N.A.
56.4
49.5
52.1
53.8
P-Site Identity:
100
0
13.3
0
N.A.
93.3
86.6
0
0
20
N.A.
6.6
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
0
40
13.3
N.A.
100
100
20
6.6
40
N.A.
20
N.A.
53.3
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
0
8
0
0
8
0
8
8
0
15
0
0
% D
% Glu:
8
22
0
8
0
8
15
8
29
15
29
15
29
22
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
15
8
0
8
% F
% Gly:
0
0
8
8
22
0
0
0
22
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
15
15
0
0
0
8
0
0
0
0
8
15
22
% I
% Lys:
8
8
8
0
0
8
15
15
15
29
8
8
0
8
0
% K
% Leu:
8
8
15
15
0
8
8
0
0
8
15
22
8
8
0
% L
% Met:
0
0
0
8
8
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
8
0
8
8
8
15
0
0
0
0
8
0
8
15
8
% N
% Pro:
0
0
0
0
15
22
29
0
8
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
8
8
8
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% R
% Ser:
8
22
15
22
15
22
0
15
0
22
0
0
0
0
22
% S
% Thr:
8
22
8
15
15
8
15
22
8
8
15
22
0
8
8
% T
% Val:
29
8
15
0
8
0
0
0
0
0
0
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _