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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MESDC2 All Species: 8.18
Human Site: T203 Identified Species: 13.85
UniProt: Q14696 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14696 NP_055969.1 234 26077 T203 G S K E K N K T K Q D K G K K
Chimpanzee Pan troglodytes XP_001161202 85 9478 K60 K T K Q D K G K K K K E G D L
Rhesus Macaque Macaca mulatta XP_001109767 149 16578 P124 F V T V S G S P T E K E T E E
Dog Lupus familis XP_545883 190 21252 K165 Q E K G K K K K E G V P K S R
Cat Felis silvestris
Mouse Mus musculus Q9ERE7 224 25188 T194 G S K E K N K T K P E K A K K
Rat Rattus norvegicus Q5U2R7 224 25197 T194 G S K E K N K T K P E K G K K
Wallaby Macropus eugenll Q9XT48 201 21518 R176 F L L T Q G D R L S T Y T D G
Platypus Ornith. anatinus XP_001514817 161 18036 K136 R N Q I K P E K K K K E G S P
Chicken Gallus gallus Q5ZKK4 220 24673 N187 D G S E K G R N K T K P E K A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1L243 206 23288 G181 N A K K D A K G K E Q N E T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T9B6 180 20983 I155 W D A K D F L I E Q E R C K G
Honey Bee Apis mellifera XP_001122588 178 21016 N153 S Q A V D A K N Y F L Q Q P E
Nematode Worm Caenorhab. elegans NP_495003 186 21786 F161 K F L L K Q E F V S E V T I E
Sea Urchin Strong. purpuratus XP_001188878 182 21140 K157 A G G K K D S K S K T K K E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.9 61.1 67.5 N.A. 83.7 81.6 21.3 59.4 74.3 N.A. 64 N.A. 38.8 30.3 34.6 38.4
Protein Similarity: 100 36.3 62.8 73.5 N.A. 90.5 88.8 35.4 64 80.3 N.A. 73.9 N.A. 56.4 49.5 52.1 53.8
P-Site Identity: 100 20 0 20 N.A. 80 86.6 0 20 26.6 N.A. 26.6 N.A. 13.3 6.6 6.6 20
P-Site Similarity: 100 46.6 26.6 33.3 N.A. 86.6 93.3 6.6 53.3 33.3 N.A. 46.6 N.A. 40 20 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 0 0 15 0 0 0 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 8 8 0 0 29 8 8 0 0 0 8 0 0 15 0 % D
% Glu: 0 8 0 29 0 0 15 0 15 15 29 22 15 15 22 % E
% Phe: 15 8 0 0 0 8 0 8 0 8 0 0 0 0 0 % F
% Gly: 22 15 8 8 0 22 8 8 0 8 0 0 29 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 0 0 0 0 0 8 0 % I
% Lys: 15 0 43 22 58 15 43 29 50 22 29 29 15 36 36 % K
% Leu: 0 8 15 8 0 0 8 0 8 0 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 22 0 15 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 8 0 15 0 15 0 8 8 % P
% Gln: 8 8 8 8 8 8 0 0 0 15 8 8 8 0 0 % Q
% Arg: 8 0 0 0 0 0 8 8 0 0 0 8 0 0 8 % R
% Ser: 8 22 8 0 8 0 15 0 8 15 0 0 0 15 0 % S
% Thr: 0 8 8 8 0 0 0 22 8 8 15 0 22 8 0 % T
% Val: 0 8 0 15 0 0 0 0 8 0 8 8 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _