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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MESDC2
All Species:
1.52
Human Site:
T45
Identified Species:
2.56
UniProt:
Q14696
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14696
NP_055969.1
234
26077
T45
P
G
T
P
D
E
S
T
P
P
P
R
K
K
K
Chimpanzee
Pan troglodytes
XP_001161202
85
9478
Rhesus Macaque
Macaca mulatta
XP_001109767
149
16578
Dog
Lupus familis
XP_545883
190
21252
K25
R
L
G
L
H
L
K
K
D
D
D
I
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERE7
224
25188
D45
P
P
P
R
K
K
K
D
I
R
D
Y
N
D
A
Rat
Rattus norvegicus
Q5U2R7
224
25197
D45
T
P
P
R
K
K
K
D
I
R
D
Y
N
D
A
Wallaby
Macropus eugenll
Q9XT48
201
21518
S36
P
N
P
D
N
S
H
S
S
S
P
A
P
P
Q
Platypus
Ornith. anatinus
XP_001514817
161
18036
Chicken
Gallus gallus
Q5ZKK4
220
24673
D46
I
R
D
Y
N
D
A
D
M
A
R
L
L
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L243
206
23288
A41
D
I
R
D
Y
N
D
A
D
M
A
R
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T9B6
180
20983
L15
L
L
L
A
L
T
P
L
V
L
A
K
K
F
K
Honey Bee
Apis mellifera
XP_001122588
178
21016
L13
I
I
Y
S
I
F
L
L
I
Y
V
N
A
N
N
Nematode Worm
Caenorhab. elegans
NP_495003
186
21786
K21
H
I
G
L
A
N
V
K
Q
K
K
K
D
L
S
Sea Urchin
Strong. purpuratus
XP_001188878
182
21140
Q17
T
L
F
V
I
I
A
Q
E
D
E
E
K
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.9
61.1
67.5
N.A.
83.7
81.6
21.3
59.4
74.3
N.A.
64
N.A.
38.8
30.3
34.6
38.4
Protein Similarity:
100
36.3
62.8
73.5
N.A.
90.5
88.8
35.4
64
80.3
N.A.
73.9
N.A.
56.4
49.5
52.1
53.8
P-Site Identity:
100
0
0
0
N.A.
6.6
0
13.3
0
0
N.A.
6.6
N.A.
13.3
0
0
6.6
P-Site Similarity:
100
0
0
13.3
N.A.
13.3
6.6
33.3
0
33.3
N.A.
13.3
N.A.
20
0
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
15
8
0
8
15
8
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
15
8
8
8
22
15
15
22
0
8
22
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
0
8
8
8
15
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
15
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
15
22
0
0
15
8
0
0
22
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
15
15
22
15
0
8
8
15
22
8
15
% K
% Leu:
8
22
8
15
8
8
8
15
0
8
0
8
15
15
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
15
15
0
0
0
0
0
8
15
8
8
% N
% Pro:
22
15
22
8
0
0
8
0
8
8
15
0
8
8
8
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
15
% Q
% Arg:
8
8
8
15
0
0
0
0
0
15
8
15
0
0
0
% R
% Ser:
0
0
0
8
0
8
8
8
8
8
0
0
0
0
8
% S
% Thr:
15
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
8
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
0
0
0
8
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _