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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GANAB All Species: 25.76
Human Site: Y379 Identified Species: 51.52
UniProt: Q14697 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14697 NP_938148.1 944 106874 Y379 I S D V F R Q Y A S L T G T Q
Chimpanzee Pan troglodytes XP_001154003 944 106938 Y379 I S D V F R Q Y A S L T G T Q
Rhesus Macaque Macaca mulatta XP_001116402 944 106915 Y379 I S D V F R Q Y A S L T G T Q
Dog Lupus familis XP_540905 966 108897 Y401 V S D V F R Q Y A S L T G T Q
Cat Felis silvestris
Mouse Mus musculus Q8BHN3 944 106893 Y379 V F D V F R Q Y A S L T G T Q
Rat Rattus norvegicus Q6P7A9 953 106188 C374 W G L G F H L C R W G Y S S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421156 914 104814 L360 G T Q A L P P L F S L G Y H Q
Frog Xenopus laevis NP_001091232 933 106071 Y369 P F D I F K Q Y A S L T G T Q
Zebra Danio Brachydanio rerio XP_002664506 941 106759 Y372 P S D V F S Q Y A S L T G T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623603 925 106819 Q369 T G T S P L P Q M F A L G Y H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 D369 M K Y I V I N D P G I G V N A
Baker's Yeast Sacchar. cerevisiae P38138 954 110248 F375 I P T I I D K F T D L T G R P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.6 90.9 N.A. 92 28.1 N.A. N.A. 50.8 68.9 65 N.A. N.A. 49 N.A. N.A.
Protein Similarity: 100 99.6 99.3 95 N.A. 96.7 43.9 N.A. N.A. 68.3 80.8 79.9 N.A. N.A. 66.2 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 86.6 6.6 N.A. N.A. 20 73.3 86.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 13.3 N.A. N.A. 26.6 86.6 86.6 N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.3 35.8 N.A.
Protein Similarity: N.A. N.A. N.A. 41.4 52.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 59 0 9 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 59 0 0 9 0 9 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 17 0 0 67 0 0 9 9 9 0 0 0 0 0 % F
% Gly: 9 17 0 9 0 0 0 0 0 9 9 17 75 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 9 % H
% Ile: 34 0 0 25 9 9 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 9 0 0 0 9 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 9 9 9 9 0 0 75 9 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % N
% Pro: 17 9 0 0 9 9 17 0 9 0 0 0 0 0 9 % P
% Gln: 0 0 9 0 0 0 59 9 0 0 0 0 0 0 67 % Q
% Arg: 0 0 0 0 0 42 0 0 9 0 0 0 0 9 0 % R
% Ser: 0 42 0 9 0 9 0 0 0 67 0 0 9 9 0 % S
% Thr: 9 9 17 0 0 0 0 0 9 0 0 67 0 59 9 % T
% Val: 17 0 0 50 9 0 0 0 0 0 0 0 9 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 59 0 0 0 9 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _