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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GANAB All Species: 21.52
Human Site: Y733 Identified Species: 43.03
UniProt: Q14697 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14697 NP_938148.1 944 106874 Y733 M R P L W V Q Y P Q D V T T F
Chimpanzee Pan troglodytes XP_001154003 944 106938 Y733 M R P L W V Q Y P Q D V T T F
Rhesus Macaque Macaca mulatta XP_001116402 944 106915 Y733 M R P L W V Q Y P Q D V T T F
Dog Lupus familis XP_540905 966 108897 Y755 M R P L W V H Y P Q D V T T F
Cat Felis silvestris
Mouse Mus musculus Q8BHN3 944 106893 Y733 M R P L W V Q Y P E D M S T F
Rat Rattus norvegicus Q6P7A9 953 106188 F731 A R P L F L E F P E D P S T W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421156 914 104814 F702 M R P L W I E F P E K L E T F
Frog Xenopus laevis NP_001091232 933 106071 F723 M R P L W V E F P S D V S T F
Zebra Danio Brachydanio rerio XP_002664506 941 106759 Y725 M R P L W V D Y P K E T A T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623603 925 106819 P713 R P L W A H Y P S E T E T Y A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 V701 S S F M I S P V L E Q G K T E
Baker's Yeast Sacchar. cerevisiae P38138 954 110248 F732 M F I E H P E F A E L Y H I D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.6 90.9 N.A. 92 28.1 N.A. N.A. 50.8 68.9 65 N.A. N.A. 49 N.A. N.A.
Protein Similarity: 100 99.6 99.3 95 N.A. 96.7 43.9 N.A. N.A. 68.3 80.8 79.9 N.A. N.A. 66.2 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 80 40 N.A. N.A. 53.3 73.3 66.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 86.6 N.A. N.A. 86.6 93.3 80 N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.3 35.8 N.A.
Protein Similarity: N.A. N.A. N.A. 41.4 52.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 0 0 9 0 0 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 0 59 0 0 0 9 % D
% Glu: 0 0 0 9 0 0 34 0 0 50 9 9 9 0 9 % E
% Phe: 0 9 9 0 9 0 0 34 0 0 0 0 0 0 67 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 9 9 9 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 9 0 9 9 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 9 0 9 0 0 % K
% Leu: 0 0 9 75 0 9 0 0 9 0 9 9 0 0 0 % L
% Met: 75 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 75 0 0 9 9 9 75 0 0 9 0 0 0 % P
% Gln: 0 0 0 0 0 0 34 0 0 34 9 0 0 0 0 % Q
% Arg: 9 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 9 0 0 0 9 0 0 9 9 0 0 25 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 9 42 84 0 % T
% Val: 0 0 0 0 0 59 0 9 0 0 0 42 0 0 0 % V
% Trp: 0 0 0 9 67 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 9 50 0 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _