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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFTN1 All Species: 12.73
Human Site: S505 Identified Species: 35
UniProt: Q14699 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14699 NP_055965.1 578 63146 S505 Q Q Q E G G V S E E M K G P V
Chimpanzee Pan troglodytes XP_516313 713 77155 S640 Q Q Q E G G V S E E M K G P V
Rhesus Macaque Macaca mulatta XP_001083771 665 72898 S592 Q Q Q E G G V S E E M K G P D
Dog Lupus familis XP_542773 613 67234 S543 P H Q E D E A S E E L K V P I
Cat Felis silvestris
Mouse Mus musculus Q6A0D4 554 61519 V493 Q F S K A G D V G N C V L G A
Rat Rattus norvegicus NP_001128483 554 61265 A493 Q F S R A G D A G N C V L G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514699 606 67324 F521 S H E V D G I F S K K A E A P
Chicken Gallus gallus Q7SZI5 602 65678 Q514 A S G P G P E Q Q L D S V I N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922593 653 73220 S590 N G Q N L P E S P E K R D Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.7 82.7 73.7 N.A. 69.5 69.1 N.A. 64.5 56.3 N.A. 31.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 80.9 84.6 78.7 N.A. 77.3 76.8 N.A. 73.7 70 N.A. 47.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 46.6 N.A. 13.3 13.3 N.A. 6.6 6.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 60 N.A. 20 20 N.A. 26.6 13.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 23 0 12 12 0 0 0 12 0 12 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 % C
% Asp: 0 0 0 0 23 0 23 0 0 0 12 0 12 0 12 % D
% Glu: 0 0 12 45 0 12 23 0 45 56 0 0 12 0 0 % E
% Phe: 0 23 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 0 12 12 0 45 67 0 0 23 0 0 0 34 23 0 % G
% His: 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 12 % I
% Lys: 0 0 0 12 0 0 0 0 0 12 23 45 0 0 0 % K
% Leu: 0 0 0 0 12 0 0 0 0 12 12 0 23 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % M
% Asn: 12 0 0 12 0 0 0 0 0 23 0 0 0 0 12 % N
% Pro: 12 0 0 12 0 23 0 0 12 0 0 0 0 45 12 % P
% Gln: 56 34 56 0 0 0 0 12 12 0 0 0 0 12 0 % Q
% Arg: 0 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % R
% Ser: 12 12 23 0 0 0 0 56 12 0 0 12 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 34 12 0 0 0 23 23 0 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _