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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNB1
All Species:
13.64
Human Site:
S590
Identified Species:
42.86
UniProt:
Q14721
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14721
NP_004966.1
858
95878
S590
R
S
M
S
S
I
D
S
F
I
S
C
A
T
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543042
858
96045
S590
R
S
M
S
S
I
D
S
F
I
S
C
A
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q03717
857
95674
S590
R
S
M
S
S
I
D
S
F
I
S
C
A
T
D
Rat
Rattus norvegicus
P15387
857
95619
S590
R
S
M
S
S
I
D
S
F
I
S
C
A
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507252
997
108259
D528
M
R
S
M
S
S
I
D
S
F
I
S
C
A
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079257
876
99069
D590
M
R
S
M
S
S
I
D
S
F
I
S
C
T
A
Zebra Danio
Brachydanio rerio
XP_682848
827
92522
M564
P
G
Q
G
G
D
P
M
N
G
G
R
E
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195169
1105
121957
G677
M
Q
L
P
D
R
F
G
G
P
S
H
R
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.4
N.A.
93.4
94
N.A.
53.7
N.A.
75.5
66.6
N.A.
N.A.
N.A.
N.A.
38.3
Protein Similarity:
100
N.A.
N.A.
98.5
N.A.
96.3
96.1
N.A.
60.5
N.A.
85
77.3
N.A.
N.A.
N.A.
N.A.
52.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
50
13
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
50
25
0
0
% C
% Asp:
0
0
0
0
13
13
50
25
0
0
0
0
0
13
63
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
13
0
50
25
0
0
0
0
0
% F
% Gly:
0
13
0
13
13
0
0
13
13
13
13
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
0
0
0
0
0
50
25
0
0
50
25
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
38
0
50
25
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% N
% Pro:
13
0
0
13
0
0
13
0
0
13
0
0
0
0
0
% P
% Gln:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
25
0
0
0
13
0
0
0
0
0
13
13
0
0
% R
% Ser:
0
50
25
50
75
25
0
50
25
0
63
25
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
13
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _