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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNB1 All Species: 4.55
Human Site: S651 Identified Species: 14.29
UniProt: Q14721 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14721 NP_004966.1 858 95878 S651 P D A S Q H S S F F I E S P K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543042 858 96045 T651 P D A S H R S T F F I E S P K
Cat Felis silvestris
Mouse Mus musculus Q03717 857 95674 F651 P E A S R S G F F V E S P R S
Rat Rattus norvegicus P15387 857 95619 F651 P E T S R S G F F V E S P R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507252 997 108259 F589 D G G R R S G F F I E S P R S
Chicken Gallus gallus
Frog Xenopus laevis NP_001079257 876 99069 P651 E S F T E V H P K T D L S R H
Zebra Danio Brachydanio rerio XP_682848 827 92522 S625 S G L S S R V S A N P S L Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195169 1105 121957 D738 G V I V Q K L D D G F T T T W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 97.4 N.A. 93.4 94 N.A. 53.7 N.A. 75.5 66.6 N.A. N.A. N.A. N.A. 38.3
Protein Similarity: 100 N.A. N.A. 98.5 N.A. 96.3 96.1 N.A. 60.5 N.A. 85 77.3 N.A. N.A. N.A. N.A. 52.9
P-Site Identity: 100 N.A. N.A. 80 N.A. 26.6 20 N.A. 6.6 N.A. 6.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 40 33.3 N.A. 13.3 N.A. 20 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 38 0 0 0 0 0 13 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 25 0 0 0 0 0 13 13 0 13 0 0 0 0 % D
% Glu: 13 25 0 0 13 0 0 0 0 0 38 25 0 0 0 % E
% Phe: 0 0 13 0 0 0 0 38 63 25 13 0 0 0 0 % F
% Gly: 13 25 13 0 0 0 38 0 0 13 0 0 0 0 0 % G
% His: 0 0 0 0 13 13 13 0 0 0 0 0 0 0 13 % H
% Ile: 0 0 13 0 0 0 0 0 0 13 25 0 0 0 0 % I
% Lys: 0 0 0 0 0 13 0 0 13 0 0 0 0 0 25 % K
% Leu: 0 0 13 0 0 0 13 0 0 0 0 13 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % N
% Pro: 50 0 0 0 0 0 0 13 0 0 13 0 38 25 0 % P
% Gln: 0 0 0 0 25 0 0 0 0 0 0 0 0 13 0 % Q
% Arg: 0 0 0 13 38 25 0 0 0 0 0 0 0 50 0 % R
% Ser: 13 13 0 63 13 38 25 25 0 0 0 50 38 0 38 % S
% Thr: 0 0 13 13 0 0 0 13 0 13 0 13 13 13 13 % T
% Val: 0 13 0 13 0 13 13 0 0 25 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _