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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
17.58
Human Site:
S223
Identified Species:
27.62
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
S223
F
F
L
R
F
L
E
S
P
D
F
Q
P
N
I
Chimpanzee
Pan troglodytes
XP_518483
668
77639
S289
F
F
L
R
F
L
E
S
P
D
F
Q
P
N
I
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
Y213
K
T
I
L
H
R
I
Y
G
K
F
L
G
L
R
Dog
Lupus familis
XP_538927
602
69962
S223
F
F
L
R
F
L
E
S
P
D
F
Q
P
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
I189
L
K
T
T
L
H
R
I
Y
G
K
F
L
G
L
Rat
Rattus norvegicus
XP_001062510
563
65413
R214
L
F
D
S
E
D
P
R
E
R
D
F
L
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
R119
F
L
K
T
I
L
H
R
I
Y
G
K
F
L
G
Chicken
Gallus gallus
XP_419321
459
53699
N124
M
V
E
Y
I
T
H
N
R
D
V
V
T
E
A
Frog
Xenopus laevis
NP_001087638
506
58853
F171
S
N
P
T
G
A
E
F
D
P
E
E
D
E
P
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
P215
L
E
S
P
D
F
Q
P
N
I
A
K
K
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
S304
L
F
L
R
F
L
E
S
P
D
F
Q
P
S
M
Honey Bee
Apis mellifera
XP_392477
724
84384
R213
D
F
Q
P
S
I
A
R
R
Y
I
D
Q
K
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
Q212
V
A
K
K
Y
I
D
Q
K
F
V
L
A
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
P175
N
I
F
R
T
L
N
P
Q
P
R
E
N
K
V
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
S396
F
F
L
R
F
V
E
S
P
D
F
N
H
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
6.6
100
N.A.
0
6.6
N.A.
13.3
6.6
6.6
6.6
N.A.
80
6.6
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
6.6
6.6
N.A.
20
13.3
13.3
20
N.A.
93.3
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
7
0
0
0
7
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
7
7
7
0
7
40
7
7
7
0
0
% D
% Glu:
0
7
7
0
7
0
40
0
7
0
7
14
0
14
0
% E
% Phe:
34
47
7
0
34
7
0
7
0
7
40
14
7
0
7
% F
% Gly:
0
0
0
0
7
0
0
0
7
7
7
0
7
7
7
% G
% His:
0
0
0
0
7
7
14
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
7
0
14
14
7
7
7
7
7
0
0
0
34
% I
% Lys:
7
7
14
7
0
0
0
0
7
7
7
14
7
20
0
% K
% Leu:
27
7
34
7
7
40
0
0
0
0
0
14
14
20
14
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
7
0
0
0
0
7
7
7
0
0
7
7
20
0
% N
% Pro:
0
0
7
14
0
0
7
14
34
14
0
0
27
0
7
% P
% Gln:
0
0
7
0
0
0
7
7
7
0
0
27
7
7
0
% Q
% Arg:
0
0
0
40
0
7
7
20
14
7
7
0
0
0
7
% R
% Ser:
7
0
7
7
7
0
0
34
0
0
0
0
0
7
0
% S
% Thr:
0
7
7
20
7
7
0
0
0
0
0
0
7
0
7
% T
% Val:
7
7
0
0
0
7
0
0
0
0
14
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
7
7
14
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _