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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5D All Species: 4.85
Human Site: S50 Identified Species: 7.62
UniProt: Q14738 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14738 NP_006236.1 602 69992 S50 Q P Q P Q A Q S Q P P S S N K
Chimpanzee Pan troglodytes XP_518483 668 77639 S116 Q P Q P Q A Q S Q P P S S N K
Rhesus Macaque Macaca mulatta XP_001087636 549 63874 I50 P P T Q L S K I K Y S G G P Q
Dog Lupus familis XP_538927 602 69962 P50 Q P Q P Q P Q P Q P P S S N K
Cat Felis silvestris
Mouse Mus musculus Q60996 524 60806 A26 N G P F Q P V A L L H I R D V
Rat Rattus norvegicus XP_001062510 563 65413 N49 Q P Q P P S S N K R P S N S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508677 454 52707
Chicken Gallus gallus XP_419321 459 53699
Frog Xenopus laevis NP_001087638 506 58853 D8 M P N K N K K D K E P P K A G
Zebra Danio Brachydanio rerio NP_998483 601 69849 P51 K R P S N S T P P P T Q L N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001138071 703 79051 L131 G T P P L S S L A N K L K D N
Honey Bee Apis mellifera XP_392477 724 84384 N50 P P P P T L I N K I K Y Q P G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780420 579 66728 R48 P P P T Q L T R T K G T G P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 K12 I L S K L P N K K S S K H E H
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 S224 T Q D A N H A S S Q S I D I P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 91 98.8 N.A. 69.9 92 N.A. 70.2 72.5 69.7 85.2 N.A. 56.9 57.1 N.A. 68.2
Protein Similarity: 100 90.1 91.1 99.3 N.A. 78 92.8 N.A. 72.7 74.5 77.5 92.1 N.A. 68.8 67.4 N.A. 79
P-Site Identity: 100 100 6.6 86.6 N.A. 6.6 40 N.A. 0 0 13.3 20 N.A. 6.6 13.3 N.A. 13.3
P-Site Similarity: 100 100 33.3 86.6 N.A. 20 73.3 N.A. 0 0 26.6 33.3 N.A. 20 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 43.8 39.7 N.A.
Protein Similarity: N.A. N.A. N.A. 58.4 53.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 14 7 7 7 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 7 0 0 0 0 7 14 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 7 0 0 0 0 0 0 0 0 7 7 14 0 14 % G
% His: 0 0 0 0 0 7 0 0 0 0 7 0 7 0 7 % H
% Ile: 7 0 0 0 0 0 7 7 0 7 0 14 0 7 0 % I
% Lys: 7 0 0 14 0 7 14 7 34 7 14 7 14 0 27 % K
% Leu: 0 7 0 0 20 14 0 7 7 7 0 7 7 0 7 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 0 20 0 7 14 0 7 0 0 7 27 7 % N
% Pro: 20 54 34 40 7 20 0 14 7 27 34 7 0 20 7 % P
% Gln: 27 7 27 7 34 0 20 0 20 7 0 7 7 0 7 % Q
% Arg: 0 7 0 0 0 0 0 7 0 7 0 0 7 0 0 % R
% Ser: 0 0 7 7 0 27 14 20 7 7 20 27 20 7 0 % S
% Thr: 7 7 7 7 7 0 14 0 7 0 7 7 0 0 7 % T
% Val: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _