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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
13.64
Human Site:
S75
Identified Species:
21.43
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
S75
Q
L
S
K
I
K
Y
S
G
G
P
Q
I
V
K
Chimpanzee
Pan troglodytes
XP_518483
668
77639
S141
Q
L
S
K
I
K
Y
S
G
G
P
Q
I
V
K
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
N75
S
R
F
N
L
S
K
N
R
E
L
Q
K
L
P
Dog
Lupus familis
XP_538927
602
69962
S75
Q
L
S
K
I
K
Y
S
G
G
P
Q
I
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
V51
Q
K
L
R
Q
C
C
V
L
F
D
F
V
S
D
Rat
Rattus norvegicus
XP_001062510
563
65413
E74
Y
S
G
G
P
Q
I
E
R
E
E
L
F
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
Chicken
Gallus gallus
XP_419321
459
53699
Frog
Xenopus laevis
NP_001087638
506
58853
S33
D
N
P
E
H
E
V
S
N
K
K
S
N
S
T
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
S76
K
K
E
R
R
Q
S
S
S
R
F
N
L
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
I156
P
I
S
K
V
L
N
I
T
G
T
P
I
V
R
Honey Bee
Apis mellifera
XP_392477
724
84384
S75
S
S
S
R
F
N
I
S
K
N
R
E
L
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
R73
R
F
N
I
S
K
N
R
E
L
Q
K
L
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
A37
S
S
S
H
T
S
G
A
S
T
S
K
S
T
D
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
D249
T
P
T
K
L
N
P
D
T
D
L
E
L
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
6.6
100
N.A.
6.6
0
N.A.
0
0
6.6
13.3
N.A.
33.3
20
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
20
20
N.A.
0
0
20
40
N.A.
53.3
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
7
0
7
7
0
0
0
14
% D
% Glu:
0
0
7
7
0
7
0
7
7
14
7
14
0
0
0
% E
% Phe:
0
7
7
0
7
0
0
0
0
7
7
7
7
0
0
% F
% Gly:
0
0
7
7
0
0
7
0
20
27
0
0
0
0
0
% G
% His:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
20
0
14
7
0
0
0
0
27
14
0
% I
% Lys:
7
14
0
34
0
27
7
0
7
7
7
14
7
0
40
% K
% Leu:
0
20
7
0
14
7
0
0
7
7
14
7
27
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
7
0
14
14
7
7
7
0
7
7
0
0
% N
% Pro:
7
7
7
0
7
0
7
0
0
0
20
7
0
7
14
% P
% Gln:
27
0
0
0
7
14
0
0
0
0
7
27
0
7
7
% Q
% Arg:
7
7
0
20
7
0
0
7
14
7
7
0
0
0
7
% R
% Ser:
20
20
40
0
7
14
7
40
14
0
7
7
7
20
0
% S
% Thr:
7
0
7
0
7
0
0
0
14
7
7
0
0
7
7
% T
% Val:
0
0
0
0
7
0
7
7
0
0
0
0
7
27
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _