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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5D All Species: 17.58
Human Site: S88 Identified Species: 27.62
UniProt: Q14738 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14738 NP_006236.1 602 69992 S88 V K K E R R Q S S S R F N L S
Chimpanzee Pan troglodytes XP_518483 668 77639 S154 V K K E R R Q S S S R F N L S
Rhesus Macaque Macaca mulatta XP_001087636 549 63874 P88 L P A L K D S P T Q E R E E L
Dog Lupus familis XP_538927 602 69962 S88 V K K E R R Q S S S R F N L S
Cat Felis silvestris
Mouse Mus musculus Q60996 524 60806 K64 S D P L S D L K W K E V K R A
Rat Rattus norvegicus XP_001062510 563 65413 C87 I Q K L R Q C C V L F D F V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508677 454 52707
Chicken Gallus gallus XP_419321 459 53699
Frog Xenopus laevis NP_001087638 506 58853 V46 S T P P P A Q V S K I K V P T
Zebra Danio Brachydanio rerio NP_998483 601 69849 K89 S K N R E L Q K L P A L K D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001138071 703 79051 T169 V R K E K R Q T S A R Y N A S
Honey Bee Apis mellifera XP_392477 724 84384 E88 Q K L P L L S E T Q Q G N E R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780420 579 66728 P86 P P L K D A T P G E R E D L F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 S50 T D N G A A K S H A K N A S P
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 S262 I K T P Q R H S S S R F E P S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 91 98.8 N.A. 69.9 92 N.A. 70.2 72.5 69.7 85.2 N.A. 56.9 57.1 N.A. 68.2
Protein Similarity: 100 90.1 91.1 99.3 N.A. 78 92.8 N.A. 72.7 74.5 77.5 92.1 N.A. 68.8 67.4 N.A. 79
P-Site Identity: 100 100 0 100 N.A. 0 20 N.A. 0 0 13.3 13.3 N.A. 60 13.3 N.A. 13.3
P-Site Similarity: 100 100 20 100 N.A. 6.6 46.6 N.A. 0 0 20 20 N.A. 93.3 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 43.8 39.7 N.A.
Protein Similarity: N.A. N.A. N.A. 58.4 53.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 20 0 0 0 14 7 0 7 7 14 % A
% Cys: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 0 7 14 0 0 0 0 0 7 7 7 0 % D
% Glu: 0 0 0 27 7 0 0 7 0 7 14 7 14 14 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 27 7 0 7 % F
% Gly: 0 0 0 7 0 0 0 0 7 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % H
% Ile: 14 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 40 34 7 14 0 7 14 0 14 7 7 14 0 0 % K
% Leu: 7 0 14 20 7 14 7 0 7 7 0 7 0 27 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 14 0 0 0 0 0 0 0 0 7 34 0 0 % N
% Pro: 7 14 14 20 7 0 0 14 0 7 0 0 0 14 7 % P
% Gln: 7 7 0 0 7 7 40 0 0 14 7 0 0 0 0 % Q
% Arg: 0 7 0 7 27 34 0 0 0 0 40 7 0 7 7 % R
% Ser: 20 0 0 0 7 0 14 34 40 27 0 0 0 7 40 % S
% Thr: 7 7 7 0 0 0 7 7 14 0 0 0 0 0 7 % T
% Val: 27 0 0 0 0 0 0 7 7 0 0 7 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _