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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
17.58
Human Site:
S95
Identified Species:
27.62
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
S95
S
S
S
R
F
N
L
S
K
N
R
E
L
Q
K
Chimpanzee
Pan troglodytes
XP_518483
668
77639
S161
S
S
S
R
F
N
L
S
K
N
R
E
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
L95
P
T
Q
E
R
E
E
L
F
I
Q
K
L
R
Q
Dog
Lupus familis
XP_538927
602
69962
S95
S
S
S
R
F
N
L
S
K
N
R
E
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
A71
K
W
K
E
V
K
R
A
A
L
S
E
M
V
E
Rat
Rattus norvegicus
XP_001062510
563
65413
S94
C
V
L
F
D
F
V
S
D
P
L
S
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
Chicken
Gallus gallus
XP_419321
459
53699
Frog
Xenopus laevis
NP_001087638
506
58853
T53
V
S
K
I
K
V
P
T
P
Q
A
V
V
K
K
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
A96
K
L
P
A
L
K
D
A
P
P
I
D
R
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
S176
T
S
A
R
Y
N
A
S
K
N
C
E
L
T
A
Honey Bee
Apis mellifera
XP_392477
724
84384
R95
E
T
Q
Q
G
N
E
R
E
E
L
F
I
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
F93
P
G
E
R
E
D
L
F
S
K
K
L
L
Q
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
P57
S
H
A
K
N
A
S
P
A
G
K
S
A
A
S
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
S269
S
S
S
R
F
E
P
S
R
Y
T
P
L
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
6.6
100
N.A.
6.6
13.3
N.A.
0
0
13.3
0
N.A.
53.3
20
N.A.
26.6
P-Site Similarity:
100
100
40
100
N.A.
26.6
20
N.A.
0
0
33.3
26.6
N.A.
73.3
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
7
0
7
7
14
14
0
7
0
7
7
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% C
% Asp:
0
0
0
0
7
7
7
0
7
0
0
7
7
0
0
% D
% Glu:
7
0
7
14
7
14
14
0
7
7
0
34
0
7
14
% E
% Phe:
0
0
0
7
27
7
0
7
7
0
0
7
0
0
0
% F
% Gly:
0
7
0
0
7
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
7
7
0
7
0
0
% I
% Lys:
14
0
14
7
7
14
0
0
27
7
14
7
0
7
47
% K
% Leu:
0
7
7
0
7
0
27
7
0
7
14
7
47
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
7
34
0
0
0
27
0
0
0
0
0
% N
% Pro:
14
0
7
0
0
0
14
7
14
14
0
7
0
0
0
% P
% Gln:
0
0
14
7
0
0
0
0
0
7
7
0
0
34
7
% Q
% Arg:
0
0
0
40
7
0
7
7
7
0
20
0
7
7
0
% R
% Ser:
34
40
27
0
0
0
7
40
7
0
7
14
0
0
7
% S
% Thr:
7
14
0
0
0
0
0
7
0
0
7
0
0
14
0
% T
% Val:
7
7
0
0
7
7
7
0
0
0
0
7
7
7
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _