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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
31.21
Human Site:
Y339
Identified Species:
49.05
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
Y339
K
V
K
S
L
S
V
Y
H
P
Q
L
A
Y
C
Chimpanzee
Pan troglodytes
XP_518483
668
77639
Y405
K
V
K
S
L
S
V
Y
H
P
Q
L
A
Y
C
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
F315
V
I
V
G
L
L
K
F
W
P
K
T
H
S
P
Dog
Lupus familis
XP_538927
602
69962
Y339
K
V
K
S
L
S
V
Y
H
P
Q
L
A
Y
C
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
K291
P
V
V
M
A
L
L
K
Y
W
P
K
T
H
S
Rat
Rattus norvegicus
XP_001062510
563
65413
L318
F
L
E
K
E
S
S
L
T
E
P
V
I
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
W221
I
V
G
L
L
K
F
W
P
K
T
H
S
P
K
Chicken
Gallus gallus
XP_419321
459
53699
I226
E
R
D
F
L
K
T
I
L
H
R
I
Y
G
K
Frog
Xenopus laevis
NP_001087638
506
58853
G273
Y
E
T
E
H
H
N
G
I
A
E
L
L
E
I
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
Y326
K
V
K
S
L
S
V
Y
H
P
Q
L
A
Y
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
Y420
K
A
K
S
L
S
V
Y
H
P
Q
L
T
Y
C
Honey Bee
Apis mellifera
XP_392477
724
84384
Y320
K
A
K
S
L
S
V
Y
H
P
Q
L
A
Y
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
Y314
K
A
K
S
L
S
V
Y
H
P
Q
L
A
Y
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
Y277
K
S
I
N
N
I
F
Y
R
F
V
F
E
T
E
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
Y512
K
V
R
C
L
S
L
Y
H
P
Q
L
A
Y
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
13.3
100
N.A.
6.6
6.6
N.A.
13.3
6.6
6.6
100
N.A.
86.6
93.3
N.A.
93.3
P-Site Similarity:
100
100
33.3
100
N.A.
26.6
26.6
N.A.
26.6
26.6
13.3
100
N.A.
86.6
93.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
7
0
0
0
0
7
0
0
47
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
54
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
7
7
7
7
0
0
0
0
7
7
0
7
7
7
% E
% Phe:
7
0
0
7
0
0
14
7
0
7
0
7
0
0
0
% F
% Gly:
0
0
7
7
0
0
0
7
0
0
0
0
0
7
7
% G
% His:
0
0
0
0
7
7
0
0
54
7
0
7
7
7
0
% H
% Ile:
7
7
7
0
0
7
0
7
7
0
0
7
7
0
7
% I
% Lys:
60
0
47
7
0
14
7
7
0
7
7
7
0
0
14
% K
% Leu:
0
7
0
7
74
14
14
7
7
0
0
60
7
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
7
60
14
0
0
7
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
0
% Q
% Arg:
0
7
7
0
0
0
0
0
7
0
7
0
0
0
0
% R
% Ser:
0
7
0
47
0
60
7
0
0
0
0
0
7
7
7
% S
% Thr:
0
0
7
0
0
0
7
0
7
0
7
7
14
7
0
% T
% Val:
7
47
14
0
0
0
47
0
0
0
7
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
7
7
7
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
60
7
0
0
0
7
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _