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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
23.94
Human Site:
Y488
Identified Species:
37.62
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
Y488
F
D
D
C
T
Q
Q
Y
K
A
E
K
Q
K
G
Chimpanzee
Pan troglodytes
XP_518483
668
77639
Y554
F
D
D
C
T
Q
Q
Y
K
A
E
K
Q
K
G
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
I456
R
E
E
M
W
Q
K
I
E
E
L
A
R
L
N
Dog
Lupus familis
XP_538927
602
69962
Y488
F
D
D
C
T
Q
Q
Y
K
A
E
K
Q
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
K432
E
R
E
E
A
W
V
K
I
E
N
L
A
K
A
Rat
Rattus norvegicus
XP_001062510
563
65413
E462
K
G
R
F
R
M
K
E
R
E
E
M
W
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
E362
E
E
M
W
H
K
V
E
E
L
A
R
L
N
P
Chicken
Gallus gallus
XP_419321
459
53699
P367
E
F
V
K
V
M
E
P
L
F
R
Q
L
A
K
Frog
Xenopus laevis
NP_001087638
506
58853
D414
Y
I
M
S
L
I
S
D
N
A
A
K
I
L
P
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
Y475
F
D
D
C
T
Q
Q
Y
K
A
E
K
Q
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
Y569
F
D
E
C
S
K
N
Y
K
Q
E
K
Q
M
E
Honey Bee
Apis mellifera
XP_392477
724
84384
Y469
F
D
E
C
T
Q
Q
Y
Y
Q
D
R
Q
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
Y463
F
D
D
C
M
Q
K
Y
K
D
E
R
Q
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
W418
A
E
R
A
L
F
L
W
N
N
N
H
I
E
N
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
N658
A
I
N
S
G
S
W
N
R
A
I
H
A
M
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
6.6
100
N.A.
6.6
6.6
N.A.
0
0
13.3
93.3
N.A.
53.3
53.3
N.A.
60
P-Site Similarity:
100
100
40
100
N.A.
13.3
26.6
N.A.
26.6
13.3
20
93.3
N.A.
73.3
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
7
7
0
0
0
0
40
14
7
14
7
14
% A
% Cys:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
34
0
0
0
0
7
0
7
7
0
0
0
0
% D
% Glu:
20
20
27
7
0
0
7
14
14
20
47
0
0
7
27
% E
% Phe:
47
7
0
7
0
7
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
20
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
14
0
0
0
% H
% Ile:
0
14
0
0
0
7
0
7
7
0
7
0
14
0
0
% I
% Lys:
7
0
0
7
0
14
20
7
40
0
0
40
0
34
14
% K
% Leu:
0
0
0
0
14
0
7
0
7
7
7
7
14
14
0
% L
% Met:
0
0
14
7
7
14
0
0
0
0
0
7
0
14
0
% M
% Asn:
0
0
7
0
0
0
7
7
14
7
14
0
0
7
14
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
14
% P
% Gln:
0
0
0
0
0
47
34
0
0
14
0
7
47
14
0
% Q
% Arg:
7
7
14
0
7
0
0
0
14
0
7
20
7
7
0
% R
% Ser:
0
0
0
14
7
7
7
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
7
0
14
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
7
7
7
7
7
0
0
0
0
7
0
0
% W
% Tyr:
7
0
0
0
0
0
0
47
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _