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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LBR All Species: 18.18
Human Site: S182 Identified Species: 28.57
UniProt: Q14739 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14739 NP_002287.2 615 70703 S182 V K L K E I D S K E E K Y V A
Chimpanzee Pan troglodytes XP_514234 615 70705 S182 V K L K E I D S K E E K Y I A
Rhesus Macaque Macaca mulatta XP_001094360 615 70652 S182 V K L K E I D S K E E K F I A
Dog Lupus familis XP_547512 618 70479 S183 I K L K D I D S K E E N I V P
Cat Felis silvestris
Mouse Mus musculus Q3U9G9 626 71422 S192 V K A K E I E S E E Q N L V T
Rat Rattus norvegicus O08984 620 70706 R187 V K P K H R V R G T N L V T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514211 617 70577 L183 V K L Q E T D L N E E T I I G
Chicken Gallus gallus P23913 637 73480 A179 K K K E E I Y A E K K I F E A
Frog Xenopus laevis Q7ZXH1 473 54804 L90 I W D K T P A L T W T A V K I
Zebra Danio Brachydanio rerio Q7SXF1 478 55171 T96 W N R A P S F T W A A A K I Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MLV1 741 83167 S211 D G E V D T D S I R K R I T E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786536 578 65964 F179 F G G P I G T F L M I F G L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDR4 369 41895
Baker's Yeast Sacchar. cerevisiae P32462 438 50597 L56 Q N F D I V E L W N G I K P L
Red Bread Mold Neurospora crassa P38670 490 54704 G108 V Q Y R F L P G H H V E G T E
Conservation
Percent
Protein Identity: 100 99 98.2 82.3 N.A. 78.7 79.5 N.A. 78.1 65.4 30.4 29.9 N.A. 23 N.A. N.A. 44.2
Protein Similarity: 100 99.8 99.3 89.4 N.A. 88 87.4 N.A. 87.3 77.3 45.8 46.1 N.A. 38.7 N.A. N.A. 59.1
P-Site Identity: 100 93.3 86.6 66.6 N.A. 53.3 20 N.A. 46.6 26.6 6.6 0 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 100 80 N.A. 73.3 20 N.A. 60 66.6 13.3 13.3 N.A. 33.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 28.2 30.5 20.6
Protein Similarity: N.A. N.A. N.A. 40.9 43.2 34.8
P-Site Identity: N.A. N.A. N.A. 0 0 6.6
P-Site Similarity: N.A. N.A. N.A. 0 13.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 7 7 0 7 7 14 0 0 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 7 14 0 40 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 7 40 0 14 0 14 40 34 7 0 7 14 % E
% Phe: 7 0 7 0 7 0 7 7 0 0 0 7 14 0 0 % F
% Gly: 0 14 7 0 0 7 0 7 7 0 7 0 14 0 7 % G
% His: 0 0 0 0 7 0 0 0 7 7 0 0 0 0 0 % H
% Ile: 14 0 0 0 14 40 0 0 7 0 7 14 20 27 7 % I
% Lys: 7 54 7 47 0 0 0 0 27 7 14 20 14 7 0 % K
% Leu: 0 0 34 0 0 7 0 20 7 0 0 7 7 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 14 0 0 0 0 0 0 7 7 7 14 0 0 0 % N
% Pro: 0 0 7 7 7 7 7 0 0 0 0 0 0 7 14 % P
% Gln: 7 7 0 7 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 7 7 0 7 0 7 0 7 0 7 0 0 7 % R
% Ser: 0 0 0 0 0 7 0 40 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 7 14 7 7 7 7 7 7 0 20 7 % T
% Val: 47 0 0 7 0 7 7 0 0 0 7 0 14 20 0 % V
% Trp: 7 7 0 0 0 0 0 0 14 7 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 0 0 0 0 0 14 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _