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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LBR All Species: 20.61
Human Site: S357 Identified Species: 32.38
UniProt: Q14739 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14739 NP_002287.2 615 70703 S357 K A P R N D L S P A S S G N A
Chimpanzee Pan troglodytes XP_514234 615 70705 S357 K A P R N D L S P A S S G N A
Rhesus Macaque Macaca mulatta XP_001094360 615 70652 S357 K A P R N D L S P A S S G N A
Dog Lupus familis XP_547512 618 70479 A360 W A P P A A L A P A S S G N A
Cat Felis silvestris
Mouse Mus musculus Q3U9G9 626 71422 S368 R A P R E E L S P A S S G N A
Rat Rattus norvegicus O08984 620 70706 S362 K V P R D E L S P A S S G N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514211 617 70577 S359 K A S K D E L S L G K S G N V
Chicken Gallus gallus P23913 637 73480 A349 K A P E E D L A P G G N S G Y
Frog Xenopus laevis Q7ZXH1 473 54804 P241 K L F F N G R P G I V A W T L
Zebra Danio Brachydanio rerio Q7SXF1 478 55171 G247 L F F N G R P G I V A W T L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MLV1 741 83167 D463 L R Q T L T N D Y G R T G S F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786536 578 65964 H336 F Y D F F M G H E L N P R L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDR4 369 41895 Q138 F G I Q L N P Q F M S I D L K
Baker's Yeast Sacchar. cerevisiae P32462 438 50597 L207 G R E L N P R L G P L D I K M
Red Bread Mold Neurospora crassa P38670 490 54704 V259 Q Y R L Y G Y V T D S I L F I
Conservation
Percent
Protein Identity: 100 99 98.2 82.3 N.A. 78.7 79.5 N.A. 78.1 65.4 30.4 29.9 N.A. 23 N.A. N.A. 44.2
Protein Similarity: 100 99.8 99.3 89.4 N.A. 88 87.4 N.A. 87.3 77.3 45.8 46.1 N.A. 38.7 N.A. N.A. 59.1
P-Site Identity: 100 100 100 66.6 N.A. 80 80 N.A. 46.6 40 13.3 0 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 100 73.3 N.A. 93.3 93.3 N.A. 66.6 53.3 20 6.6 N.A. 20 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 28.2 30.5 20.6
Protein Similarity: N.A. N.A. N.A. 40.9 43.2 34.8
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 20 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 47 0 0 7 7 0 14 0 40 7 7 0 0 40 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 14 27 0 7 0 7 0 7 7 0 0 % D
% Glu: 0 0 7 7 14 20 0 0 7 0 0 0 0 0 0 % E
% Phe: 14 7 14 14 7 0 0 0 7 0 0 0 0 7 7 % F
% Gly: 7 7 0 0 7 14 7 7 14 20 7 0 54 7 7 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 7 7 0 14 7 0 14 % I
% Lys: 47 0 0 7 0 0 0 0 0 0 7 0 0 7 7 % K
% Leu: 14 7 0 14 14 0 54 7 7 7 7 0 7 20 7 % L
% Met: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 7 % M
% Asn: 0 0 0 7 34 7 7 0 0 0 7 7 0 47 0 % N
% Pro: 0 0 47 7 0 7 14 7 47 7 0 7 0 0 0 % P
% Gln: 7 0 7 7 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 7 14 7 34 0 7 14 0 0 0 7 0 7 0 0 % R
% Ser: 0 0 7 0 0 0 0 40 0 0 54 47 7 7 0 % S
% Thr: 0 0 0 7 0 7 0 0 7 0 0 7 7 7 0 % T
% Val: 0 7 0 0 0 0 0 7 0 7 7 0 0 0 7 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % W
% Tyr: 0 14 0 0 7 0 7 0 7 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _