Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LBR All Species: 36.67
Human Site: Y602 Identified Species: 57.62
UniProt: Q14739 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14739 NP_002287.2 615 70703 Y602 Y G V A W E K Y C Q R V P Y R
Chimpanzee Pan troglodytes XP_514234 615 70705 Y602 Y G V A W E K Y R Q R V P Y R
Rhesus Macaque Macaca mulatta XP_001094360 615 70652 Y602 Y G V A W E K Y C Q R V P Y R
Dog Lupus familis XP_547512 618 70479 Y605 Y G L A W E K Y C Q R V P Y R
Cat Felis silvestris
Mouse Mus musculus Q3U9G9 626 71422 Y613 Y G L A W E K Y C Q R V P Y R
Rat Rattus norvegicus O08984 620 70706 Y607 Y G L A W E K Y C Q R V P Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514211 617 70577 Y604 Y G L A W E K Y C Q C V P Y R
Chicken Gallus gallus P23913 637 73480 Y595 Y G L A W E R Y C Q R V P Y T
Frog Xenopus laevis Q7ZXH1 473 54804 Y460 Y G K D W K L Y T S A V P Y R
Zebra Danio Brachydanio rerio Q7SXF1 478 55171 T466 G K D W E R Y T A A V S Y R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MLV1 741 83167 R727 R Y H S S W Q R Y S T Q V R S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786536 578 65964 Y565 Y G G A W T K Y C A T V K Y R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDR4 369 41895 L357 K E I W A E Y L R L V P W R I
Baker's Yeast Sacchar. cerevisiae P32462 438 50597 E426 G E N W E E Y E R K V P Y K I
Red Bread Mold Neurospora crassa P38670 490 54704 K478 G D D W E K Y K K L V K W R I
Conservation
Percent
Protein Identity: 100 99 98.2 82.3 N.A. 78.7 79.5 N.A. 78.1 65.4 30.4 29.9 N.A. 23 N.A. N.A. 44.2
Protein Similarity: 100 99.8 99.3 89.4 N.A. 88 87.4 N.A. 87.3 77.3 45.8 46.1 N.A. 38.7 N.A. N.A. 59.1
P-Site Identity: 100 93.3 100 93.3 N.A. 93.3 93.3 N.A. 86.6 80 53.3 0 N.A. 0 N.A. N.A. 66.6
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 93.3 93.3 60 0 N.A. 13.3 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. 28.2 30.5 20.6
Protein Similarity: N.A. N.A. N.A. 40.9 43.2 34.8
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 0
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 60 7 0 0 0 7 14 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 54 0 7 0 0 0 0 % C
% Asp: 0 7 14 7 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 14 0 0 20 67 0 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 67 7 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 20 % I
% Lys: 7 7 7 0 0 14 54 7 7 7 0 7 7 7 0 % K
% Leu: 0 0 34 0 0 0 7 7 0 14 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 14 60 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 54 0 7 0 0 0 % Q
% Arg: 7 0 0 0 0 7 7 7 20 0 47 0 0 27 60 % R
% Ser: 0 0 0 7 7 0 0 0 0 14 0 7 0 0 7 % S
% Thr: 0 0 0 0 0 7 0 7 7 0 14 0 0 0 7 % T
% Val: 0 0 20 0 0 0 0 0 0 0 27 67 7 0 0 % V
% Trp: 0 0 0 27 67 7 0 0 0 0 0 0 14 0 0 % W
% Tyr: 67 7 0 0 0 0 27 67 7 0 0 0 14 67 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _