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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG2
All Species:
8.79
Human Site:
S118
Identified Species:
24.17
UniProt:
Q14746
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14746
NP_031383.1
738
83208
S118
R
A
V
D
E
R
M
S
K
Q
E
D
I
R
K
Chimpanzee
Pan troglodytes
XP_001148147
738
83195
S118
R
A
V
D
E
R
M
S
K
Q
E
D
I
R
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546096
715
80302
V114
C
V
L
R
L
I
Q
V
I
R
S
V
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q921L5
731
82023
S118
L
A
V
D
E
R
M
S
K
Q
E
D
I
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF78
710
81117
D114
E
S
I
H
G
L
I
D
E
N
V
T
E
L
R
Honey Bee
Apis mellifera
XP_625092
679
79564
L92
I
N
D
L
Q
T
P
L
G
Q
L
R
E
E
V
Nematode Worm
Caenorhab. elegans
Q21444
681
78546
L94
L
V
S
L
Q
D
S
L
N
K
I
E
Q
D
I
Sea Urchin
Strong. purpuratus
XP_794127
744
83614
A120
Q
D
V
E
E
K
M
A
T
R
N
R
T
R
Q
Poplar Tree
Populus trichocarpa
XP_002322242
757
84096
E133
V
A
L
K
N
G
L
E
Q
R
S
E
A
A
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.3
N.A.
85.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
32.6
31.2
22.3
49.7
Protein Similarity:
100
99.5
N.A.
93.2
N.A.
92.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
52.7
54.3
43.3
66.8
P-Site Identity:
100
100
N.A.
0
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
6.6
0
26.6
P-Site Similarity:
100
100
N.A.
20
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
13.3
20
66.6
Percent
Protein Identity:
29
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
50.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
45
0
0
0
0
0
12
0
0
0
0
12
12
12
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
34
0
12
0
12
0
0
0
34
0
12
0
% D
% Glu:
12
0
0
12
45
0
0
12
12
0
34
23
34
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
12
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
12
0
0
12
12
0
12
0
12
0
34
0
23
% I
% Lys:
0
0
0
12
0
12
0
0
34
12
0
0
0
12
34
% K
% Leu:
23
0
23
23
12
12
12
23
0
0
12
0
0
12
0
% L
% Met:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
12
0
0
0
12
12
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
23
0
12
0
12
45
0
0
12
0
12
% Q
% Arg:
23
0
0
12
0
34
0
0
0
34
0
23
0
45
12
% R
% Ser:
0
12
12
0
0
0
12
34
0
0
23
0
0
0
0
% S
% Thr:
0
0
0
0
0
12
0
0
12
0
0
12
12
0
0
% T
% Val:
12
23
45
0
0
0
0
12
0
0
12
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _