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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNMT
All Species:
18.48
Human Site:
S252
Identified Species:
40.67
UniProt:
Q14749
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14749
NP_061833.1
295
32742
S252
Y
Y
P
H
C
L
A
S
F
T
E
L
L
Q
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089876
295
32693
S252
Y
Y
P
H
C
L
A
S
F
T
E
L
L
Q
A
Dog
Lupus familis
XP_532140
295
32695
S252
Y
Y
P
H
R
L
A
S
F
T
E
L
L
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXF8
293
32657
S250
Y
Y
P
H
C
L
A
S
F
T
E
L
V
R
A
Rat
Rattus norvegicus
P13255
293
32531
S250
Y
Y
P
H
C
L
A
S
F
T
E
L
V
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508790
588
65253
P545
Y
Y
P
H
R
L
V
P
F
T
E
L
L
R
E
Chicken
Gallus gallus
XP_001232829
531
58160
A488
Y
Y
P
H
R
L
E
A
F
T
A
L
L
K
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997981
294
33227
E251
S
Y
Y
P
H
R
V
E
N
F
K
E
I
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650223
289
32665
R247
Y
Y
P
H
G
L
K
R
F
Q
E
I
L
A
E
Honey Bee
Apis mellifera
XP_625210
292
33740
S250
S
Y
Y
P
H
K
L
S
V
F
T
E
I
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784229
290
32784
H248
P
I
A
P
V
H
V
H
E
F
T
A
L
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
96.2
N.A.
91.8
91.5
N.A.
39.6
38.9
N.A.
72.5
N.A.
56.9
57.9
N.A.
36.6
Protein Similarity:
100
N.A.
99.6
97.2
N.A.
95.5
95.9
N.A.
45.2
47
N.A.
83.3
N.A.
72.1
72.1
N.A.
53.2
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
86.6
N.A.
66.6
60
N.A.
6.6
N.A.
53.3
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
93.3
N.A.
73.3
73.3
N.A.
20
N.A.
60
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
46
10
0
0
10
10
0
10
37
% A
% Cys:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
10
10
10
0
64
19
0
0
28
% E
% Phe:
0
0
0
0
0
0
0
0
73
28
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
73
19
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
10
19
0
0
% I
% Lys:
0
0
0
0
0
10
10
0
0
0
10
0
0
10
19
% K
% Leu:
0
0
0
0
0
73
10
0
0
0
0
64
64
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
73
28
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
28
0
% Q
% Arg:
0
0
0
0
28
10
0
10
0
0
0
0
0
28
0
% R
% Ser:
19
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
64
19
0
0
0
0
% T
% Val:
0
0
0
0
10
0
28
0
10
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
73
91
19
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _