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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNMT
All Species:
30.61
Human Site:
T186
Identified Species:
67.33
UniProt:
Q14749
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14749
NP_061833.1
295
32742
T186
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089876
295
32693
T186
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
K
Dog
Lupus familis
XP_532140
295
32695
T186
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXF8
293
32657
T184
N
Y
D
Y
I
L
S
T
G
C
A
P
P
G
K
Rat
Rattus norvegicus
P13255
293
32531
T184
N
Y
D
Y
I
L
S
T
G
C
A
P
P
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508790
588
65253
T479
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
K
Chicken
Gallus gallus
XP_001232829
531
58160
T422
N
Y
D
H
I
L
A
T
G
C
A
P
P
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997981
294
33227
T185
N
Y
D
Y
I
I
E
T
G
Q
V
P
Q
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650223
289
32665
R181
G
V
L
L
I
D
H
R
N
Y
D
N
I
L
E
Honey Bee
Apis mellifera
XP_625210
292
33740
E184
R
N
Y
D
F
I
I
E
T
G
N
I
P
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784229
290
32784
M182
D
H
R
N
L
D
S
M
L
D
H
G
I
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
96.2
N.A.
91.8
91.5
N.A.
39.6
38.9
N.A.
72.5
N.A.
56.9
57.9
N.A.
36.6
Protein Similarity:
100
N.A.
99.6
97.2
N.A.
95.5
95.9
N.A.
45.2
47
N.A.
83.3
N.A.
72.1
72.1
N.A.
53.2
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
93.3
N.A.
60
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
73.3
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
64
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% C
% Asp:
10
0
73
10
0
19
0
0
0
10
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
73
10
0
10
0
73
0
% G
% His:
0
10
0
46
0
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
82
19
10
0
0
0
0
10
19
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% K
% Leu:
0
0
10
10
10
64
0
0
10
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
73
10
0
10
0
0
0
0
10
0
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
73
73
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% Q
% Arg:
10
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
64
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
73
10
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
73
10
28
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _