Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNMT All Species: 33.94
Human Site: T220 Identified Species: 74.67
UniProt: Q14749 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14749 NP_061833.1 295 32742 T220 N N K A H M V T L D Y T V Q V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089876 295 32693 T220 N N K A H M V T L D Y T V Q V
Dog Lupus familis XP_532140 295 32695 T220 N N K A H M V T L D Y T V Q V
Cat Felis silvestris
Mouse Mus musculus Q9QXF8 293 32657 T218 N N K A H M V T L D Y T V Q V
Rat Rattus norvegicus P13255 293 32531 T218 N N K A H M V T L D Y T V Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508790 588 65253 T513 N N A A H M V T L D Y T V Q V
Chicken Gallus gallus XP_001232829 531 58160 T456 N N K A H M V T L D Y T V Q V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997981 294 33227 T219 N S K P H M I T L D Y T L V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650223 289 32665 C215 K T S V L F Y C G K P A L V S
Honey Bee Apis mellifera XP_625210 292 33740 T218 S G K P A I V T L D Y I I T M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784229 290 32784 R216 E K D G V R Q R V D I I Y H L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 96.2 N.A. 91.8 91.5 N.A. 39.6 38.9 N.A. 72.5 N.A. 56.9 57.9 N.A. 36.6
Protein Similarity: 100 N.A. 99.6 97.2 N.A. 95.5 95.9 N.A. 45.2 47 N.A. 83.3 N.A. 72.1 72.1 N.A. 53.2
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 100 N.A. 60 N.A. 0 40 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 100 N.A. 86.6 N.A. 6.6 66.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 64 10 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 91 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 73 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 10 10 0 0 0 10 19 10 0 0 % I
% Lys: 10 10 73 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 82 0 0 0 19 0 19 % L
% Met: 0 0 0 0 0 73 0 0 0 0 0 0 0 0 10 % M
% Asn: 73 64 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 19 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 64 0 % Q
% Arg: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % R
% Ser: 10 10 10 0 0 0 0 0 0 0 0 0 0 0 10 % S
% Thr: 0 10 0 0 0 0 0 82 0 0 0 73 0 10 0 % T
% Val: 0 0 0 10 10 0 73 0 10 0 0 0 64 19 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 82 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _