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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MVP
All Species:
3.03
Human Site:
S445
Identified Species:
8.33
UniProt:
Q14764
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14764
NP_005106.2
893
99327
S445
G
E
K
D
T
A
K
S
L
Q
P
L
A
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536910
888
99064
T445
G
E
K
E
M
S
K
T
P
Q
P
S
V
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQK5
861
95934
V445
G
Q
K
G
T
A
K
V
L
Q
P
S
A
A
R
Rat
Rattus norvegicus
Q62667
861
95780
P445
G
Q
K
G
T
A
K
P
L
Q
P
S
A
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517120
862
95634
K444
D
R
G
G
A
G
M
K
T
S
S
H
P
P
R
Chicken
Gallus gallus
Q5ZMI4
849
93804
P446
G
I
Q
S
S
S
G
P
S
F
G
V
Q
E
R
Frog
Xenopus laevis
Q6PF69
849
95651
Q442
D
R
S
E
R
Q
G
Q
A
Q
E
V
Q
P
R
Zebra Danio
Brachydanio rerio
Q6P3L0
863
96511
R459
A
D
R
S
D
R
G
R
S
F
G
Q
A
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116989
857
95906
D447
E
R
S
D
R
R
G
D
R
A
A
P
R
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.3
N.A.
88.2
88.1
N.A.
79.9
67
68.9
67.6
N.A.
N.A.
N.A.
N.A.
64.5
Protein Similarity:
100
N.A.
N.A.
94
N.A.
92.7
91.9
N.A.
88.3
79.1
81.4
80
N.A.
N.A.
N.A.
N.A.
78.5
P-Site Identity:
100
N.A.
N.A.
46.6
N.A.
66.6
73.3
N.A.
13.3
13.3
20
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
66.6
N.A.
73.3
80
N.A.
13.3
40
33.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
34
0
0
12
12
12
0
45
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
12
0
23
12
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
12
23
0
23
0
0
0
0
0
0
12
0
0
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% F
% Gly:
56
0
12
34
0
12
45
0
0
0
23
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
45
0
0
0
45
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
34
0
0
12
0
0
0
% L
% Met:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
23
12
0
45
12
12
45
0
% P
% Gln:
0
23
12
0
0
12
0
12
0
56
0
12
23
0
0
% Q
% Arg:
0
34
12
0
23
23
0
12
12
0
0
0
12
0
100
% R
% Ser:
0
0
23
23
12
23
0
12
23
12
12
34
0
0
0
% S
% Thr:
0
0
0
0
34
0
0
12
12
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
23
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _