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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBX2 All Species: 5.45
Human Site: S126 Identified Species: 12
UniProt: Q14781 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14781 NP_005180.1 532 56081 S126 S S D E E D D S D L D A K R G
Chimpanzee Pan troglodytes XP_523736 378 42282
Rhesus Macaque Macaca mulatta XP_001108961 553 57727 S149 S S D E E D D S D L D A K R G
Dog Lupus familis XP_540468 494 51429 P106 G R E T H P V P Q K K A Q I L
Cat Felis silvestris
Mouse Mus musculus P30658 519 54872 D126 S S D E E E D D S D L D S K R
Rat Rattus norvegicus NP_001100541 523 55474 D126 S S D E E E E D D D D S D L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517212 309 33652
Chicken Gallus gallus XP_423911 497 51247 Q105 P V P Q K K A Q I L V A K P E
Frog Xenopus laevis NP_001081900 471 51271 S95 I P L K A K S S S S S S S S S
Zebra Danio Brachydanio rerio NP_919354 510 55469 H124 D D D D E D D H N M T P K P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34618 304 33765
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 88.2 81 N.A. 83.2 81.9 N.A. 46.9 56 45.6 43.4 N.A. N.A. N.A. 21.7 N.A.
Protein Similarity: 100 37.5 90.2 83.8 N.A. 86.2 85.5 N.A. 51.1 65.4 58.4 55.2 N.A. N.A. N.A. 33.8 N.A.
P-Site Identity: 100 0 100 6.6 N.A. 40 46.6 N.A. 0 20 6.6 33.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 0 100 20 N.A. 53.3 66.6 N.A. 0 33.3 20 53.3 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 0 0 0 37 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 46 10 0 28 37 19 28 19 28 10 10 0 10 % D
% Glu: 0 0 10 37 46 19 10 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % G
% His: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % I
% Lys: 0 0 0 10 10 19 0 0 0 10 10 0 37 10 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 28 10 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 10 10 10 0 0 10 0 10 0 0 0 10 0 19 0 % P
% Gln: 0 0 0 10 0 0 0 10 10 0 0 0 10 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 19 10 % R
% Ser: 37 37 0 0 0 0 10 28 19 10 10 19 19 10 10 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 10 0 0 0 0 10 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _