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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF22
All Species:
23.33
Human Site:
Y180
Identified Species:
51.33
UniProt:
Q14807
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14807
NP_015556.1
665
73262
Y180
T
M
S
Y
L
E
I
Y
Q
E
K
V
L
D
L
Chimpanzee
Pan troglodytes
XP_510910
679
74714
Y180
T
M
S
Y
L
E
I
Y
Q
E
K
V
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001104365
657
72278
V173
L
E
I
Y
Q
E
K
V
L
D
L
L
D
A
T
Dog
Lupus familis
XP_547058
651
71817
P173
K
V
L
D
L
L
E
P
T
S
G
D
L
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3V300
660
73171
Y175
A
M
S
Y
L
E
I
Y
Q
E
K
V
L
D
L
Rat
Rattus norvegicus
Q5I0E8
657
73037
Y172
A
M
S
Y
L
E
I
Y
Q
E
K
V
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYL5
650
73149
Y171
T
M
S
Y
V
E
I
Y
Q
E
K
V
M
D
L
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
R174
G
S
Q
D
L
P
I
R
E
D
K
D
R
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
H172
L
L
K
P
N
S
K
H
L
E
V
R
E
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
Y213
S
H
S
I
F
T
V
Y
V
E
G
M
T
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPC6
894
98404
Y195
S
V
S
Y
L
Q
L
Y
M
E
T
I
Q
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.8
90
N.A.
81.3
81
N.A.
N.A.
N.A.
52.3
50.9
N.A.
29.2
N.A.
28.1
N.A.
Protein Similarity:
100
97.5
96.2
93
N.A.
88.7
88.8
N.A.
N.A.
N.A.
69.3
66.1
N.A.
46.1
N.A.
45.7
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
86.6
20
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
26.6
26.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
100
46.6
N.A.
20
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
0
0
0
19
0
19
10
55
0
% D
% Glu:
0
10
0
0
0
55
10
0
10
73
0
0
10
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
19
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
55
0
0
0
0
10
0
0
19
% I
% Lys:
10
0
10
0
0
0
19
0
0
0
55
0
0
0
0
% K
% Leu:
19
10
10
0
64
10
10
0
19
0
10
10
46
0
55
% L
% Met:
0
46
0
0
0
0
0
0
10
0
0
10
10
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
10
10
0
0
46
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
10
10
10
0
% R
% Ser:
19
10
64
0
0
10
0
0
0
10
0
0
0
0
0
% S
% Thr:
28
0
0
0
0
10
0
0
10
0
10
0
10
0
19
% T
% Val:
0
19
0
0
10
0
10
10
10
0
10
46
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
64
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _