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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2D
All Species:
27.58
Human Site:
S149
Identified Species:
50.56
UniProt:
Q14814
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14814
NP_005911.1
521
55938
S149
M
P
V
T
V
P
V
S
N
Q
S
S
L
Q
F
Chimpanzee
Pan troglodytes
XP_001165500
521
55889
S149
M
P
V
T
V
P
V
S
N
Q
S
S
L
Q
F
Rhesus Macaque
Macaca mulatta
XP_001103222
500
53974
T147
M
S
V
T
V
P
V
T
S
P
N
A
L
S
Y
Dog
Lupus familis
XP_547534
525
56508
V149
E
S
P
E
V
D
E
V
F
A
L
T
P
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q63943
514
54974
S149
M
P
V
T
V
P
V
S
N
Q
S
S
M
Q
F
Rat
Rattus norvegicus
O89038
507
54350
S149
M
P
V
T
V
P
V
S
N
Q
S
S
M
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507540
505
54598
P149
V
T
V
P
V
T
N
P
N
A
L
S
Y
S
N
Chicken
Gallus gallus
Q9W6U8
499
53650
T151
V
P
V
S
N
P
N
T
L
T
Y
S
N
P
G
Frog
Xenopus laevis
Q03413
498
54053
T149
M
P
V
T
V
P
V
T
N
Q
N
A
L
H
F
Zebra Danio
Brachydanio rerio
NP_571392
529
57466
S149
M
P
V
T
V
P
V
S
N
Q
S
P
L
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
L149
L
P
N
S
S
Y
T
L
P
V
S
V
P
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
Baker's Yeast
Sacchar. cerevisiae
Q12224
676
73465
K149
S
N
M
H
S
N
K
K
A
S
D
K
N
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
53.7
72.5
N.A.
96.1
94.4
N.A.
54.1
54.7
73.6
70.1
N.A.
28
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
63.9
75.8
N.A.
97.1
95.5
N.A.
64.8
64.3
82.5
78.2
N.A.
39.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
46.6
13.3
N.A.
93.3
93.3
N.A.
26.6
26.6
73.3
86.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
20
N.A.
100
100
N.A.
33.3
46.6
93.3
86.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.9
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
16
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
47
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
8
8
0
16
0
39
0
0
% L
% Met:
54
0
8
0
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
8
8
0
8
8
16
0
54
0
16
0
16
0
8
% N
% Pro:
0
62
8
8
0
62
0
8
8
8
0
8
16
16
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
47
0
0
0
39
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
16
0
16
16
0
0
39
8
8
47
47
0
16
0
% S
% Thr:
0
8
0
54
0
8
8
24
0
8
0
8
0
0
8
% T
% Val:
16
0
70
0
70
0
54
8
0
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _