KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2D
All Species:
18.48
Human Site:
S180
Identified Species:
33.89
UniProt:
Q14814
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14814
NP_005911.1
521
55938
S180
L
T
D
P
R
L
L
S
P
Q
Q
P
A
L
Q
Chimpanzee
Pan troglodytes
XP_001165500
521
55889
S180
L
T
D
P
R
L
L
S
P
Q
Q
P
A
L
Q
Rhesus Macaque
Macaca mulatta
XP_001103222
500
53974
L178
T
L
T
D
S
S
M
L
S
P
P
Q
T
T
L
Dog
Lupus familis
XP_547534
525
56508
V180
S
Y
R
L
A
S
A
V
P
A
P
N
F
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q63943
514
54974
S180
L
T
D
P
R
L
L
S
P
Q
Q
P
A
L
Q
Rat
Rattus norvegicus
O89038
507
54350
S180
L
T
D
P
R
L
L
S
P
Q
Q
P
A
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507540
505
54598
P180
A
D
T
S
M
L
S
P
P
Q
A
T
L
H
R
Chicken
Gallus gallus
Q9W6U8
499
53650
Q182
T
T
M
L
S
P
P
Q
T
T
L
H
R
N
V
Frog
Xenopus laevis
Q03413
498
54053
S180
L
T
D
P
R
L
L
S
P
P
Q
P
S
L
Q
Zebra Danio
Brachydanio rerio
NP_571392
529
57466
P180
T
D
P
R
L
L
S
P
Q
Q
P
Q
L
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
S180
T
N
I
S
P
R
P
S
S
S
E
T
D
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
Baker's Yeast
Sacchar. cerevisiae
Q12224
676
73465
R180
D
G
S
E
Q
N
K
R
H
P
E
N
A
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
53.7
72.5
N.A.
96.1
94.4
N.A.
54.1
54.7
73.6
70.1
N.A.
28
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
63.9
75.8
N.A.
97.1
95.5
N.A.
64.8
64.3
82.5
78.2
N.A.
39.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
100
100
N.A.
20
6.6
86.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
6.6
N.A.
100
100
N.A.
26.6
6.6
93.3
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.9
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
0
0
8
8
0
39
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
39
8
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
16
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
39
8
0
16
8
54
39
8
0
0
8
0
16
47
8
% L
% Met:
0
0
8
0
8
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
16
0
8
0
% N
% Pro:
0
0
8
39
8
8
16
16
54
24
24
39
0
0
8
% P
% Gln:
0
0
0
0
8
0
0
8
8
47
39
16
0
8
39
% Q
% Arg:
0
0
8
8
39
8
0
8
0
0
0
0
8
0
16
% R
% Ser:
8
0
8
16
16
16
16
47
16
8
0
0
8
8
0
% S
% Thr:
31
47
16
0
0
0
0
0
8
8
0
16
8
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _