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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2D All Species: 14.85
Human Site: S471 Identified Species: 27.22
UniProt: Q14814 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14814 NP_005911.1 521 55938 S471 P E P G D G L S S P A G G S Y
Chimpanzee Pan troglodytes XP_001165500 521 55889 S471 P E P G D G L S S P A G G S Y
Rhesus Macaque Macaca mulatta XP_001103222 500 53974 L451 G R S P V D S L S S S S S S Y
Dog Lupus familis XP_547534 525 56508 A474 E P E A E G P A V K R M R L D
Cat Felis silvestris
Mouse Mus musculus Q63943 514 54974 S464 P E P G E G L S S P A G G S Y
Rat Rattus norvegicus O89038 507 54350 S457 P E P G E G L S S P A G G S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507540 505 54598 L456 G R S P V D S L S S S S S S Y
Chicken Gallus gallus Q9W6U8 499 53650 L450 G R S P V D S L S S S S S S Y
Frog Xenopus laevis Q03413 498 54053 L449 G R S P V D S L S S N A S S F
Zebra Danio Brachydanio rerio NP_571392 529 57466 N475 P V D S I S S N G S S Y E G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 R477 K Y E G Y P Y R A L M G H N P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 A219 Q L G L P G E A H D R R T N E
Baker's Yeast Sacchar. cerevisiae Q12224 676 73465 S585 N N S S N N N S N N G N D N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 53.7 72.5 N.A. 96.1 94.4 N.A. 54.1 54.7 73.6 70.1 N.A. 28 N.A. N.A. N.A.
Protein Similarity: 100 99.8 63.9 75.8 N.A. 97.1 95.5 N.A. 64.8 64.3 82.5 78.2 N.A. 39.5 N.A. N.A. N.A.
P-Site Identity: 100 100 20 6.6 N.A. 93.3 93.3 N.A. 20 20 13.3 6.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 20 N.A. 100 100 N.A. 26.6 26.6 20 20 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.2 22.1 N.A.
Protein Similarity: N.A. N.A. N.A. 34.9 38.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 16 8 0 31 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 16 31 0 0 0 8 0 0 8 0 8 % D
% Glu: 8 31 16 0 24 0 8 0 0 0 0 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 31 0 8 39 0 47 0 0 8 0 8 39 31 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 8 0 8 0 0 31 31 0 8 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % M
% Asn: 8 8 0 0 8 8 8 8 8 8 8 8 0 24 8 % N
% Pro: 39 8 31 31 8 8 8 0 0 31 0 0 0 0 8 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 31 0 0 0 0 0 8 0 0 16 8 8 0 0 % R
% Ser: 0 0 39 16 0 8 39 39 62 39 31 24 31 62 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % T
% Val: 0 8 0 0 31 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 8 0 0 0 0 8 0 0 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _