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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM3 All Species: 18.18
Human Site: S452 Identified Species: 33.33
UniProt: Q14832 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14832 NP_000831.2 879 98879 S452 N P N K D A D S I V K F D T F
Chimpanzee Pan troglodytes A3QNZ8 839 95029 D443 I F F D P Q G D V A L H L E I
Rhesus Macaque Macaca mulatta XP_001107588 879 98905 S452 N P N K D A D S I V K F D T F
Dog Lupus familis XP_541867 872 95696 E440 R P A D T H S E V R F D R F G
Cat Felis silvestris
Mouse Mus musculus Q9QYS2 879 99096 S452 N P N K G A D S I V K F D T Y
Rat Rattus norvegicus P31422 879 98942 S452 N P N K G A D S I V K F D T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515487 775 87278 H381 Y A Y L K V G H W A E S L T L
Chicken Gallus gallus XP_416842 879 98936 S452 N P P N A A D S T V K F D A Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 Y449 N G D I N L G Y D L F L W E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 D480 C P D M A N Y D G K E F Y N N
Honey Bee Apis mellifera NP_001011624 933 103448 E482 G S E V K F D E H G D G L A R
Nematode Worm Caenorhab. elegans Q09630 999 113258 N518 Q N Y L L K V N F T G K T I S
Sea Urchin Strong. purpuratus XP_784936 1474 165598 S1023 D T E V S F D S Q G D G L G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.9 99.5 68.7 N.A. 96.6 96.5 N.A. 79.1 91 N.A. 26.5 N.A. 46 48.2 39.4 33.3
Protein Similarity: 100 45.3 99.6 82.3 N.A. 98.7 98.5 N.A. 83.8 95.4 N.A. 46 N.A. 61.6 64.7 57.1 44.9
P-Site Identity: 100 0 100 6.6 N.A. 86.6 93.3 N.A. 6.6 60 N.A. 6.6 N.A. 13.3 6.6 0 13.3
P-Site Similarity: 100 6.6 100 13.3 N.A. 93.3 93.3 N.A. 13.3 66.6 N.A. 26.6 N.A. 26.6 6.6 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 16 39 0 0 0 16 0 0 0 16 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 16 16 16 0 54 16 8 0 16 8 39 0 0 % D
% Glu: 0 0 16 0 0 0 0 16 0 0 16 0 0 16 0 % E
% Phe: 0 8 8 0 0 16 0 0 8 0 16 47 0 8 24 % F
% Gly: 8 8 0 0 16 0 24 0 8 16 8 16 0 8 16 % G
% His: 0 0 0 0 0 8 0 8 8 0 0 8 0 0 0 % H
% Ile: 8 0 0 8 0 0 0 0 31 0 0 0 0 8 8 % I
% Lys: 0 0 0 31 16 8 0 0 0 8 39 8 0 0 0 % K
% Leu: 0 0 0 16 8 8 0 0 0 8 8 8 31 0 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 47 8 31 8 8 8 0 8 0 0 0 0 0 8 8 % N
% Pro: 0 54 8 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 16 % R
% Ser: 0 8 0 0 8 0 8 47 0 0 0 8 0 0 8 % S
% Thr: 0 8 0 0 8 0 0 0 8 8 0 0 8 39 0 % T
% Val: 0 0 0 16 0 8 8 0 16 39 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % W
% Tyr: 8 0 16 0 0 0 8 8 0 0 0 0 8 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _