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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM3
All Species:
23.94
Human Site:
S491
Identified Species:
43.89
UniProt:
Q14832
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14832
NP_000831.2
879
98879
S491
G
H
W
A
E
T
L
S
L
D
V
N
S
I
H
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
S482
L
K
N
I
Q
D
I
S
W
H
T
I
N
N
T
Rhesus Macaque
Macaca mulatta
XP_001107588
879
98905
S491
G
H
W
A
E
T
L
S
L
D
V
N
S
I
H
Dog
Lupus familis
XP_541867
872
95696
T479
G
Y
W
A
E
G
L
T
L
D
T
S
L
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYS2
879
99096
Y491
G
H
W
A
E
T
L
Y
L
D
V
D
S
I
H
Rat
Rattus norvegicus
P31422
879
98942
S491
G
H
W
A
E
T
L
S
L
D
V
D
S
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515487
775
87278
G420
E
M
K
N
M
Q
P
G
D
V
C
C
W
I
C
Chicken
Gallus gallus
XP_416842
879
98936
S491
G
H
W
A
E
T
L
S
L
E
V
D
S
I
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
K488
H
N
D
L
S
E
I
K
K
V
V
S
R
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
Y519
A
R
Y
D
I
L
N
Y
Q
R
Q
E
N
S
S
Honey Bee
Apis mellifera
NP_001011624
933
103448
R521
W
F
N
S
L
D
I
R
T
E
E
L
I
W
A
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
I557
D
G
P
A
S
Y
T
I
L
T
Y
K
P
K
S
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
S1062
N
I
L
S
M
N
L
S
A
V
H
F
H
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.9
99.5
68.7
N.A.
96.6
96.5
N.A.
79.1
91
N.A.
26.5
N.A.
46
48.2
39.4
33.3
Protein Similarity:
100
45.3
99.6
82.3
N.A.
98.7
98.5
N.A.
83.8
95.4
N.A.
46
N.A.
61.6
64.7
57.1
44.9
P-Site Identity:
100
6.6
100
53.3
N.A.
86.6
93.3
N.A.
6.6
86.6
N.A.
6.6
N.A.
0
0
13.3
13.3
P-Site Similarity:
100
26.6
100
73.3
N.A.
93.3
100
N.A.
6.6
100
N.A.
26.6
N.A.
13.3
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
54
0
0
0
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
8
% C
% Asp:
8
0
8
8
0
16
0
0
8
39
0
24
0
0
0
% D
% Glu:
8
0
0
0
47
8
0
0
0
16
8
8
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
47
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% G
% His:
8
39
0
0
0
0
0
0
0
8
8
0
8
0
39
% H
% Ile:
0
8
0
8
8
0
24
8
0
0
0
8
8
54
0
% I
% Lys:
0
8
8
0
0
0
0
8
8
0
0
8
0
8
0
% K
% Leu:
8
0
8
8
8
8
54
0
54
0
0
8
8
0
0
% L
% Met:
0
8
0
0
16
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
16
8
0
8
8
0
0
0
0
16
16
8
0
% N
% Pro:
0
0
8
0
0
0
8
0
0
0
0
0
8
8
8
% P
% Gln:
0
0
0
0
8
8
0
0
8
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
8
0
0
8
0
0
% R
% Ser:
0
0
0
16
16
0
0
47
0
0
0
16
39
8
24
% S
% Thr:
0
0
0
0
0
39
8
8
8
8
16
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
24
47
0
0
0
0
% V
% Trp:
8
0
47
0
0
0
0
0
8
0
0
0
8
8
0
% W
% Tyr:
0
8
8
0
0
8
0
16
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _