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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM3 All Species: 29.09
Human Site: T118 Identified Species: 53.33
UniProt: Q14832 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14832 NP_000831.2 879 98879 T118 E F V R A S L T K V D E A E Y
Chimpanzee Pan troglodytes A3QNZ8 839 95029 D100 L L G Y E I V D V C Y I S N N
Rhesus Macaque Macaca mulatta XP_001107588 879 98905 T118 E F V R A S L T K V D E A E Y
Dog Lupus familis XP_541867 872 95696 S111 D F V R A S L S R G A D G S R
Cat Felis silvestris
Mouse Mus musculus Q9QYS2 879 99096 T118 E F V R A S L T K V D E A E Y
Rat Rattus norvegicus P31422 879 98942 T118 E F V R A S L T K V D E A E Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515487 775 87278 S66 L F Q I P Q I S Y A S T S A K
Chicken Gallus gallus XP_416842 879 98936 T118 E F V R A S L T K V D E T E Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 T113 D T C S D V T T A L R A V H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 N123 Q F V R A S L N N L D T S G Y
Honey Bee Apis mellifera NP_001011624 933 103448 S134 H F V R A S L S N L D M S V L
Nematode Worm Caenorhab. elegans Q09630 999 113258 G167 D F V R D M I G S S E A S D Y
Sea Urchin Strong. purpuratus XP_784936 1474 165598 T688 E F V R V S L T T S N P A D C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.9 99.5 68.7 N.A. 96.6 96.5 N.A. 79.1 91 N.A. 26.5 N.A. 46 48.2 39.4 33.3
Protein Similarity: 100 45.3 99.6 82.3 N.A. 98.7 98.5 N.A. 83.8 95.4 N.A. 46 N.A. 61.6 64.7 57.1 44.9
P-Site Identity: 100 0 100 40 N.A. 100 100 N.A. 6.6 93.3 N.A. 6.6 N.A. 53.3 46.6 26.6 53.3
P-Site Similarity: 100 13.3 100 66.6 N.A. 100 100 N.A. 26.6 93.3 N.A. 20 N.A. 73.3 66.6 60 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 62 0 0 0 8 8 8 16 39 8 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 8 % C
% Asp: 24 0 0 0 16 0 0 8 0 0 54 8 0 16 8 % D
% Glu: 47 0 0 0 8 0 0 0 0 0 8 39 0 39 0 % E
% Phe: 0 85 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 8 0 8 0 0 8 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 8 0 8 16 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 39 0 0 0 0 0 8 % K
% Leu: 16 8 0 0 0 0 70 0 0 24 0 0 0 0 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 16 0 8 0 0 8 8 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 8 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 77 0 0 0 0 8 0 8 0 0 0 8 % R
% Ser: 0 0 0 8 0 70 0 24 8 16 8 0 39 8 0 % S
% Thr: 0 8 0 0 0 0 8 54 8 0 0 16 8 0 0 % T
% Val: 0 0 77 0 8 8 8 0 8 39 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 8 0 8 0 0 0 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _