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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM3 All Species: 23.03
Human Site: Y125 Identified Species: 42.22
UniProt: Q14832 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14832 NP_000831.2 879 98879 Y125 T K V D E A E Y M C P D G S Y
Chimpanzee Pan troglodytes A3QNZ8 839 95029 N107 D V C Y I S N N V Q P V L Y F
Rhesus Macaque Macaca mulatta XP_001107588 879 98905 Y125 T K V D E A E Y M C P D G S Y
Dog Lupus familis XP_541867 872 95696 R118 S R G A D G S R H I C P D G S
Cat Felis silvestris
Mouse Mus musculus Q9QYS2 879 99096 Y125 T K V D E A E Y M C P D G S Y
Rat Rattus norvegicus P31422 879 98942 Y125 T K V D E A E Y M C P D G S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515487 775 87278 K73 S Y A S T S A K L S D K S R Y
Chicken Gallus gallus XP_416842 879 98936 Y125 T K V D E T E Y M C P D G S Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 D120 T A L R A V H D I M R P F S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 Y130 N N L D T S G Y E C A D G S S
Honey Bee Apis mellifera NP_001011624 933 103448 L141 S N L D M S V L E C A D R S A
Nematode Worm Caenorhab. elegans Q09630 999 113258 Y174 G S S E A S D Y V C L D G S D
Sea Urchin Strong. purpuratus XP_784936 1474 165598 C695 T T S N P A D C L N K S T I V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.9 99.5 68.7 N.A. 96.6 96.5 N.A. 79.1 91 N.A. 26.5 N.A. 46 48.2 39.4 33.3
Protein Similarity: 100 45.3 99.6 82.3 N.A. 98.7 98.5 N.A. 83.8 95.4 N.A. 46 N.A. 61.6 64.7 57.1 44.9
P-Site Identity: 100 6.6 100 0 N.A. 100 100 N.A. 6.6 93.3 N.A. 13.3 N.A. 40 26.6 33.3 13.3
P-Site Similarity: 100 26.6 100 20 N.A. 100 100 N.A. 26.6 93.3 N.A. 26.6 N.A. 53.3 46.6 60 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 16 39 8 0 0 0 16 0 0 0 8 % A
% Cys: 0 0 8 0 0 0 0 8 0 62 8 0 0 0 0 % C
% Asp: 8 0 0 54 8 0 16 8 0 0 8 62 8 0 16 % D
% Glu: 0 0 0 8 39 0 39 0 16 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % F
% Gly: 8 0 8 0 0 8 8 0 0 0 0 0 54 8 0 % G
% His: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 8 0 0 0 8 0 % I
% Lys: 0 39 0 0 0 0 0 8 0 0 8 8 0 0 0 % K
% Leu: 0 0 24 0 0 0 0 8 16 0 8 0 8 0 0 % L
% Met: 0 0 0 0 8 0 0 0 39 8 0 0 0 0 0 % M
% Asn: 8 16 0 8 0 0 8 8 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 47 16 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 8 0 8 0 0 0 8 0 0 8 0 8 8 0 % R
% Ser: 24 8 16 8 0 39 8 0 0 8 0 8 8 70 16 % S
% Thr: 54 8 0 0 16 8 0 0 0 0 0 0 8 0 0 % T
% Val: 0 8 39 0 0 8 8 0 16 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 54 0 0 0 0 0 8 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _