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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM3 All Species: 28.18
Human Site: Y569 Identified Species: 51.67
UniProt: Q14832 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14832 NP_000831.2 879 98879 Y569 C Y D L P E D Y I R W E D A W
Chimpanzee Pan troglodytes A3QNZ8 839 95029 E548 N E W S Y Q S E T S C F K R Q
Rhesus Macaque Macaca mulatta XP_001107588 879 98905 Y569 C Y D L P E D Y I R W E D A W
Dog Lupus familis XP_541867 872 95696 Y560 C F E L P Q E Y I R W G D A W
Cat Felis silvestris
Mouse Mus musculus Q9QYS2 879 99096 Y569 C Y N L P E D Y I R W E D A W
Rat Rattus norvegicus P31422 879 98942 Y569 C Y N L P E D Y I K W E D A W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515487 775 87278 C486 I A C L G F M C T C A V V T V
Chicken Gallus gallus XP_416842 879 98936 Y569 C Y D L P E D Y I K W E D A W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 Y558 C H P K V F E Y F D W N S G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 Y619 C Y A L D I Q Y M K W N S L F
Honey Bee Apis mellifera NP_001011624 933 103448 H598 C Y Q L A I N H I R W N S A F
Nematode Worm Caenorhab. elegans Q09630 999 113258 Y674 L S L S Q L K Y M R W R S M Y
Sea Urchin Strong. purpuratus XP_784936 1474 165598 H1143 C Y K L A K Q H M D W V S V Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.9 99.5 68.7 N.A. 96.6 96.5 N.A. 79.1 91 N.A. 26.5 N.A. 46 48.2 39.4 33.3
Protein Similarity: 100 45.3 99.6 82.3 N.A. 98.7 98.5 N.A. 83.8 95.4 N.A. 46 N.A. 61.6 64.7 57.1 44.9
P-Site Identity: 100 0 100 66.6 N.A. 93.3 86.6 N.A. 6.6 93.3 N.A. 20 N.A. 33.3 46.6 20 26.6
P-Site Similarity: 100 6.6 100 93.3 N.A. 100 100 N.A. 6.6 100 N.A. 40 N.A. 53.3 66.6 33.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 16 0 0 0 0 0 8 0 0 54 0 % A
% Cys: 77 0 8 0 0 0 0 8 0 8 8 0 0 0 0 % C
% Asp: 0 0 24 0 8 0 39 0 0 16 0 0 47 0 0 % D
% Glu: 0 8 8 0 0 39 16 8 0 0 0 39 0 0 0 % E
% Phe: 0 8 0 0 0 16 0 0 8 0 0 8 0 0 24 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 8 0 8 0 % G
% His: 0 8 0 0 0 0 0 16 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 16 0 0 54 0 0 0 0 0 0 % I
% Lys: 0 0 8 8 0 8 8 0 0 24 0 0 8 0 0 % K
% Leu: 8 0 8 77 0 8 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 8 0 24 0 0 0 0 8 0 % M
% Asn: 8 0 16 0 0 0 8 0 0 0 0 24 0 0 0 % N
% Pro: 0 0 8 0 47 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 8 16 16 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 47 0 8 0 8 0 % R
% Ser: 0 8 0 16 0 0 8 0 0 8 0 0 39 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 16 0 0 0 0 8 0 % T
% Val: 0 0 0 0 8 0 0 0 0 0 0 16 8 8 8 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 85 0 0 0 47 % W
% Tyr: 0 62 0 0 8 0 0 70 0 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _