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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM4 All Species: 19.09
Human Site: T389 Identified Species: 42
UniProt: Q14833 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14833 NP_000832.1 912 101868 T389 G S H V K K C T N R E R I G Q
Chimpanzee Pan troglodytes A3QNZ8 839 95029 P333 T I Q S V P I P G F S E F R E
Rhesus Macaque Macaca mulatta XP_001088843 908 101770 T385 N S H I K K C T G L E R I A R
Dog Lupus familis XP_538870 865 96059 R342 L P K R M S V R D R E R I G Q
Cat Felis silvestris
Mouse Mus musculus Q68EF4 912 101805 T389 G S H I K K C T N R E R I G Q
Rat Rattus norvegicus P31423 912 101800 T389 G S H I K K C T N R E R I G Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508620 908 101703 T385 N S H I K K C T G L E R I A R
Chicken Gallus gallus XP_425426 924 103611 T385 N S N I K K C T G L E R I A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 F363 N N S F L K E F L K L N A G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 D401 V K A K T E C D D S Y R L S E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09630 999 113258 R439 P P G S T A S R C E D I K Q S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.1 74.8 93.1 N.A. 97 97.1 N.A. 74.2 72.4 N.A. 27.2 N.A. 44.1 N.A. 36.5 N.A.
Protein Similarity: 100 42.8 85.3 93.8 N.A. 98 98.1 N.A. 84.6 83.8 N.A. 45.9 N.A. 60.4 N.A. 54.6 N.A.
P-Site Identity: 100 0 60 40 N.A. 93.3 93.3 N.A. 60 53.3 N.A. 13.3 N.A. 13.3 N.A. 0 N.A.
P-Site Similarity: 100 6.6 73.3 46.6 N.A. 100 100 N.A. 73.3 73.3 N.A. 26.6 N.A. 40 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 0 0 0 0 10 28 0 % A
% Cys: 0 0 0 0 0 0 64 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 19 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 10 0 0 10 64 10 0 0 19 % E
% Phe: 0 0 0 10 0 0 0 10 0 10 0 0 10 0 0 % F
% Gly: 28 0 10 0 0 0 0 0 37 0 0 0 0 46 0 % G
% His: 0 0 46 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 46 0 0 10 0 0 0 0 10 64 0 0 % I
% Lys: 0 10 10 10 55 64 0 0 0 10 0 0 10 0 0 % K
% Leu: 10 0 0 0 10 0 0 0 10 28 10 0 10 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 37 10 10 0 0 0 0 0 28 0 0 10 0 0 10 % N
% Pro: 10 19 0 0 0 10 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 37 % Q
% Arg: 0 0 0 10 0 0 0 19 0 37 0 73 0 10 28 % R
% Ser: 0 55 10 19 0 10 10 0 0 10 10 0 0 10 10 % S
% Thr: 10 0 0 0 19 0 0 55 0 0 0 0 0 0 0 % T
% Val: 10 0 0 10 10 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _