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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM4
All Species:
27.58
Human Site:
Y449
Identified Species:
60.67
UniProt:
Q14833
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14833
NP_000832.1
912
101868
Y449
D
G
T
Q
L
L
K
Y
I
R
N
V
N
F
S
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
R378
L
S
F
N
T
I
L
R
L
S
G
E
R
V
V
Rhesus Macaque
Macaca mulatta
XP_001088843
908
101770
Y445
D
G
K
E
L
L
G
Y
I
R
A
V
N
F
N
Dog
Lupus familis
XP_538870
865
96059
Y402
D
G
T
Q
L
L
K
Y
I
R
S
V
N
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q68EF4
912
101805
Y449
D
G
T
Q
L
L
K
Y
I
R
N
V
N
F
S
Rat
Rattus norvegicus
P31423
912
101800
Y449
D
G
T
Q
L
L
K
Y
I
R
N
V
N
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508620
908
101703
Y445
D
G
K
E
L
L
S
Y
I
R
A
V
N
F
N
Chicken
Gallus gallus
XP_425426
924
103611
Y445
D
G
K
E
L
L
T
Y
I
R
A
V
N
F
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
R408
V
A
K
L
C
A
E
R
Q
C
Q
D
S
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
Y488
G
K
E
F
Y
N
N
Y
L
L
N
V
S
F
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
S529
K
T
I
S
I
F
S
S
F
R
L
S
P
F
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.1
74.8
93.1
N.A.
97
97.1
N.A.
74.2
72.4
N.A.
27.2
N.A.
44.1
N.A.
36.5
N.A.
Protein Similarity:
100
42.8
85.3
93.8
N.A.
98
98.1
N.A.
84.6
83.8
N.A.
45.9
N.A.
60.4
N.A.
54.6
N.A.
P-Site Identity:
100
0
66.6
93.3
N.A.
100
100
N.A.
66.6
66.6
N.A.
0
N.A.
26.6
N.A.
20
N.A.
P-Site Similarity:
100
13.3
80
100
N.A.
100
100
N.A.
80
80
N.A.
20
N.A.
40
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
28
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
64
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
10
28
0
0
10
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
10
10
0
10
0
0
10
0
0
0
0
82
0
% F
% Gly:
10
64
0
0
0
0
10
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
10
0
0
64
0
0
0
0
0
10
% I
% Lys:
10
10
37
0
0
0
37
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
10
64
64
10
0
19
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
10
0
0
0
37
0
64
0
28
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
37
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
0
73
0
0
10
0
0
% R
% Ser:
0
10
0
10
0
0
19
10
0
10
10
10
19
0
46
% S
% Thr:
0
10
37
0
10
0
10
0
0
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
73
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _