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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD4 All Species: 13.64
Human Site: S108 Identified Species: 25
UniProt: Q14839 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14839 NP_001264.2 1912 217991 S108 L R S D S E G S D Y T P G K K
Chimpanzee Pan troglodytes XP_001162478 1893 216259 K97 D Y T P G K K K K K K L G P K
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 S108 L R S D S E G S D Y T P G K K
Dog Lupus familis XP_534909 1912 217966 S108 L R S D S E G S D Y T P G K K
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 S101 L R S D S E G S D Y T P G K K
Rat Rattus norvegicus Q9JIX5 2581 290674 V138 Q G N P F M G V S A T A V S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 Q122 H G S G A S G Q M G V Y P S M
Frog Xenopus laevis NP_001080504 1893 214670 K98 G S D Y T P G K K K K K K M T
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 L206 V V S G G T V L N A T S P A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 K99 V E Y P S T S K R G R K R K E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 D97 A I G L T D V D V D Y E Q E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 99.7 99.3 N.A. 98.1 22.8 N.A. N.A. 22.6 84.5 23.1 N.A. 55.7 N.A. 43.2 N.A.
Protein Similarity: 100 98.9 99.7 99.5 N.A. 98.6 36.9 N.A. N.A. 35 90.5 38.4 N.A. 69.5 N.A. 59.2 N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 13.3 N.A. N.A. 13.3 6.6 13.3 N.A. 13.3 N.A. 0 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 20 N.A. N.A. 20 13.3 33.3 N.A. 26.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.6 26.4 N.A.
Protein Similarity: N.A. N.A. N.A. 43.4 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 0 0 16 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 31 0 8 0 8 31 8 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 31 0 0 0 0 0 8 0 8 16 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 16 8 16 16 0 54 0 0 16 0 0 39 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 8 24 16 16 16 16 8 39 39 % K
% Leu: 31 0 0 8 0 0 0 8 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 8 % M
% Asn: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 24 0 8 0 0 0 0 0 31 16 8 8 % P
% Gln: 8 0 0 0 0 0 0 8 0 0 0 0 8 0 8 % Q
% Arg: 0 31 0 0 0 0 0 0 8 0 8 0 8 0 0 % R
% Ser: 0 8 47 0 39 8 8 31 8 0 0 8 0 16 0 % S
% Thr: 0 0 8 0 16 16 0 0 0 0 47 0 0 0 8 % T
% Val: 16 8 0 0 0 0 16 8 8 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 8 0 0 0 0 0 31 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _