KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD4
All Species:
20
Human Site:
S1576
Identified Species:
36.67
UniProt:
Q14839
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14839
NP_001264.2
1912
217991
S1576
N
S
L
K
E
E
E
S
I
E
G
E
K
E
V
Chimpanzee
Pan troglodytes
XP_001162478
1893
216259
S1557
N
S
L
K
E
E
E
S
I
E
G
E
K
E
V
Rhesus Macaque
Macaca mulatta
XP_001107319
1912
217912
S1576
N
S
L
K
E
E
E
S
I
E
G
E
K
E
V
Dog
Lupus familis
XP_534909
1912
217966
S1576
N
S
L
K
E
E
E
S
V
E
G
E
K
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
S1569
N
S
L
K
E
E
E
S
T
E
G
E
K
E
V
Rat
Rattus norvegicus
Q9JIX5
2581
290674
L2072
D
D
D
S
D
S
E
L
D
L
S
K
L
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
K2177
S
T
E
Q
T
E
S
K
V
E
G
S
E
N
P
Frog
Xenopus laevis
NP_001080504
1893
214670
T1566
E
V
P
V
K
E
E
T
T
D
N
E
V
K
P
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
N2089
V
W
K
K
S
K
N
N
G
P
S
E
R
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
K1576
E
K
G
E
D
K
D
K
D
S
E
K
E
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
E1473
L
A
S
E
V
K
V
E
E
E
P
K
A
P
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
A1121
S
L
S
A
A
E
Q
A
G
L
Q
G
Q
N
G
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
G1205
I
R
D
D
P
F
L
G
I
T
D
K
I
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.7
99.3
N.A.
98.1
22.8
N.A.
N.A.
22.6
84.5
23.1
N.A.
55.7
N.A.
43.2
N.A.
Protein Similarity:
100
98.9
99.7
99.5
N.A.
98.6
36.9
N.A.
N.A.
35
90.5
38.4
N.A.
69.5
N.A.
59.2
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
N.A.
20
20
13.3
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
N.A.
53.3
46.6
46.6
N.A.
46.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.6
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.4
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
16
8
16
0
8
0
16
8
8
0
0
0
8
% D
% Glu:
16
0
8
16
39
62
54
8
8
54
8
54
16
39
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
0
0
8
16
0
47
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
31
0
0
0
8
0
0
% I
% Lys:
0
8
8
47
8
24
0
16
0
0
0
31
39
24
0
% K
% Leu:
8
8
39
0
0
0
8
8
0
16
0
0
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
39
0
0
0
0
0
8
8
0
0
8
0
0
16
0
% N
% Pro:
0
0
8
0
8
0
0
0
0
8
8
0
0
8
24
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
8
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
16
39
16
8
8
8
8
39
0
8
16
8
0
8
0
% S
% Thr:
0
8
0
0
8
0
0
8
16
8
0
0
0
0
0
% T
% Val:
8
8
0
8
8
0
8
0
16
0
0
0
8
0
39
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _