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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD4
All Species:
29.09
Human Site:
S309
Identified Species:
53.33
UniProt:
Q14839
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14839
NP_001264.2
1912
217991
S309
G
S
K
R
K
R
S
S
S
E
D
D
D
L
D
Chimpanzee
Pan troglodytes
XP_001162478
1893
216259
S290
G
S
K
R
K
R
S
S
S
E
D
D
D
L
D
Rhesus Macaque
Macaca mulatta
XP_001107319
1912
217912
S309
G
S
K
R
K
R
S
S
S
E
D
D
D
L
D
Dog
Lupus familis
XP_534909
1912
217966
S309
G
S
K
R
K
R
S
S
S
E
D
D
D
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
S302
G
S
K
R
K
R
S
S
S
E
D
D
D
L
D
Rat
Rattus norvegicus
Q9JIX5
2581
290674
S413
A
G
S
S
Q
G
A
S
S
G
L
S
V
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
S373
H
Q
Q
P
I
H
P
S
G
S
L
N
Q
M
N
Frog
Xenopus laevis
NP_001080504
1893
214670
S299
G
S
K
R
K
R
S
S
S
E
E
E
D
I
D
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
N408
L
L
L
Q
P
Q
S
N
T
V
S
S
A
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
E316
K
S
D
D
S
A
D
E
K
E
A
P
V
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
A290
C
T
R
A
Y
H
V
A
C
I
D
E
N
M
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
T35
F
V
P
K
K
D
R
T
F
E
Q
V
E
A
I
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
S119
K
S
Q
S
E
K
Q
S
T
V
K
I
P
T
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.7
99.3
N.A.
98.1
22.8
N.A.
N.A.
22.6
84.5
23.1
N.A.
55.7
N.A.
43.2
N.A.
Protein Similarity:
100
98.9
99.7
99.5
N.A.
98.6
36.9
N.A.
N.A.
35
90.5
38.4
N.A.
69.5
N.A.
59.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
6.6
80
6.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
33.3
100
33.3
N.A.
13.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.6
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.4
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
8
8
0
0
8
0
8
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
8
0
0
0
47
39
47
0
47
% D
% Glu:
0
0
0
0
8
0
0
8
0
62
8
16
8
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
47
8
0
0
0
8
0
0
8
8
0
0
0
8
8
% G
% His:
8
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
0
8
0
8
8
% I
% Lys:
16
0
47
8
54
8
0
0
8
0
8
0
0
0
8
% K
% Leu:
8
8
8
0
0
0
0
0
0
0
16
0
0
39
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
8
% N
% Pro:
0
0
8
8
8
0
8
0
0
0
0
8
8
0
0
% P
% Gln:
0
8
16
8
8
8
8
0
0
0
8
0
8
0
0
% Q
% Arg:
0
0
8
47
0
47
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
62
8
16
8
0
54
70
54
8
8
16
0
8
8
% S
% Thr:
0
8
0
0
0
0
0
8
16
0
0
0
0
8
0
% T
% Val:
0
8
0
0
0
0
8
0
0
16
0
8
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _