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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD4 All Species: 23.64
Human Site: S339 Identified Species: 43.33
UniProt: Q14839 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14839 NP_001264.2 1912 217991 S339 S D G S T S R S S R S R K K L
Chimpanzee Pan troglodytes XP_001162478 1893 216259 S320 S D G S T S R S S R S R K K L
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 S339 S D G S T S R S S R S R K K L
Dog Lupus familis XP_534909 1912 217966 S339 S D G S T S R S S R S R K K L
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 S332 S D G S T S R S S R S R K K L
Rat Rattus norvegicus Q9JIX5 2581 290674 K443 C A P H T A G K T G M E E N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 K403 P P P M S P M K A M S N P A G
Frog Xenopus laevis NP_001080504 1893 214670 S329 S D G S T S K S S R S R K K L
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 A438 T S G T T T T A A S S G V R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 A346 A P V V R K K A K T K I G N K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 E320 G P D V L I V E E E P A K A N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 N65 S T N L V S C N T C T Y A F H
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 S149 S D D D L L E S E D D Y G S E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 99.7 99.3 N.A. 98.1 22.8 N.A. N.A. 22.6 84.5 23.1 N.A. 55.7 N.A. 43.2 N.A.
Protein Similarity: 100 98.9 99.7 99.5 N.A. 98.6 36.9 N.A. N.A. 35 90.5 38.4 N.A. 69.5 N.A. 59.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. N.A. 6.6 93.3 26.6 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. N.A. 20 100 66.6 N.A. 20 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.6 26.4 N.A.
Protein Similarity: N.A. N.A. N.A. 43.4 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 0 16 16 0 0 8 8 16 0 % A
% Cys: 8 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % C
% Asp: 0 54 16 8 0 0 0 0 0 8 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 8 16 8 0 8 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 0 54 0 0 0 8 0 0 8 0 8 16 0 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 8 16 16 8 0 8 0 54 47 8 % K
% Leu: 0 0 0 8 16 8 0 0 0 0 0 0 0 0 54 % L
% Met: 0 0 0 8 0 0 8 0 0 8 8 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 8 0 0 0 8 0 16 8 % N
% Pro: 8 24 16 0 0 8 0 0 0 0 8 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 39 0 0 47 0 47 0 8 8 % R
% Ser: 62 8 0 47 8 54 0 54 47 8 62 0 0 8 0 % S
% Thr: 8 8 0 8 62 8 8 0 16 8 8 0 0 0 0 % T
% Val: 0 0 8 16 8 0 8 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _