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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD4 All Species: 25.45
Human Site: S340 Identified Species: 46.67
UniProt: Q14839 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14839 NP_001264.2 1912 217991 S340 D G S T S R S S R S R K K L R
Chimpanzee Pan troglodytes XP_001162478 1893 216259 S321 D G S T S R S S R S R K K L R
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 S340 D G S T S R S S R S R K K L R
Dog Lupus familis XP_534909 1912 217966 S340 D G S T S R S S R S R K K L R
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 S333 D G S T S R S S R S R K K L R
Rat Rattus norvegicus Q9JIX5 2581 290674 T444 A P H T A G K T G M E E N R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 A404 P P M S P M K A M S N P A G T
Frog Xenopus laevis NP_001080504 1893 214670 S330 D G S T S K S S R S R K K L K
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 A439 S G T T T T A A S S G V R L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 K347 P V V R K K A K T K I G N K F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 E321 P D V L I V E E E P A K A N M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 T66 T N L V S C N T C T Y A F H A
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 E150 D D D L L E S E D D Y G S E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 99.7 99.3 N.A. 98.1 22.8 N.A. N.A. 22.6 84.5 23.1 N.A. 55.7 N.A. 43.2 N.A.
Protein Similarity: 100 98.9 99.7 99.5 N.A. 98.6 36.9 N.A. N.A. 35 90.5 38.4 N.A. 69.5 N.A. 59.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. 6.6 86.6 26.6 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. N.A. 20 100 60 N.A. 13.3 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.6 26.4 N.A.
Protein Similarity: N.A. N.A. N.A. 43.4 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 16 16 0 0 8 8 16 0 16 % A
% Cys: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % C
% Asp: 54 16 8 0 0 0 0 0 8 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 8 16 8 0 8 8 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % F
% Gly: 0 54 0 0 0 8 0 0 8 0 8 16 0 8 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 8 16 16 8 0 8 0 54 47 8 8 % K
% Leu: 0 0 8 16 8 0 0 0 0 0 0 0 0 54 0 % L
% Met: 0 0 8 0 0 8 0 0 8 8 0 0 0 0 8 % M
% Asn: 0 8 0 0 0 0 8 0 0 0 8 0 16 8 0 % N
% Pro: 24 16 0 0 8 0 0 0 0 8 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 39 0 0 47 0 47 0 8 8 47 % R
% Ser: 8 0 47 8 54 0 54 47 8 62 0 0 8 0 0 % S
% Thr: 8 0 8 62 8 8 0 16 8 8 0 0 0 0 8 % T
% Val: 0 8 16 8 0 8 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _