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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD4
All Species:
25.15
Human Site:
S428
Identified Species:
46.11
UniProt:
Q14839
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14839
NP_001264.2
1912
217991
S428
W
E
A
K
E
D
N
S
E
G
E
E
I
L
E
Chimpanzee
Pan troglodytes
XP_001162478
1893
216259
S409
W
E
A
K
E
D
N
S
E
G
E
E
I
L
E
Rhesus Macaque
Macaca mulatta
XP_001107319
1912
217912
S428
W
E
A
K
E
D
N
S
E
G
E
E
I
L
E
Dog
Lupus familis
XP_534909
1912
217966
S428
W
E
A
K
E
D
N
S
E
G
E
E
I
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
S421
W
E
A
K
E
D
N
S
E
G
E
E
I
L
E
Rat
Rattus norvegicus
Q9JIX5
2581
290674
T527
K
T
A
A
A
S
K
T
K
G
K
S
K
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
P553
H
Q
S
P
Q
N
T
P
Q
K
V
P
V
L
Q
Frog
Xenopus laevis
NP_001080504
1893
214670
S419
W
E
A
K
E
D
N
S
E
L
D
D
D
L
D
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
A532
S
K
K
K
S
P
S
A
G
G
A
K
M
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
D433
G
A
A
E
E
E
D
D
D
E
H
Q
E
F
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
E405
L
E
C
K
E
G
E
E
A
S
K
D
D
V
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
E148
L
H
C
S
W
V
P
E
K
E
F
Q
K
A
Y
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
S232
N
T
W
E
T
Y
E
S
I
G
Q
V
R
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.7
99.3
N.A.
98.1
22.8
N.A.
N.A.
22.6
84.5
23.1
N.A.
55.7
N.A.
43.2
N.A.
Protein Similarity:
100
98.9
99.7
99.5
N.A.
98.6
36.9
N.A.
N.A.
35
90.5
38.4
N.A.
69.5
N.A.
59.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
6.6
66.6
13.3
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
N.A.
53.3
86.6
53.3
N.A.
46.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.6
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.4
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
62
8
8
0
0
8
8
0
8
0
0
8
0
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
47
8
8
8
0
8
16
16
0
8
% D
% Glu:
0
54
0
16
62
8
16
16
47
16
39
39
8
0
39
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% F
% Gly:
8
0
0
0
0
8
0
0
8
62
0
0
0
8
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
39
0
0
% I
% Lys:
8
8
8
62
0
0
8
0
16
8
16
8
16
0
0
% K
% Leu:
16
0
0
0
0
0
0
0
0
8
0
0
0
62
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
0
8
47
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
8
8
8
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
8
0
0
0
8
0
8
16
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
8
8
8
8
8
54
0
8
0
8
0
0
0
% S
% Thr:
0
16
0
0
8
0
8
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
8
8
8
16
8
% V
% Trp:
47
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _