KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD4
All Species:
29.7
Human Site:
Y649
Identified Species:
54.44
UniProt:
Q14839
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14839
NP_001264.2
1912
217991
Y649
I
K
W
R
D
L
P
Y
D
Q
A
S
W
E
S
Chimpanzee
Pan troglodytes
XP_001162478
1893
216259
Y630
I
K
W
R
D
L
P
Y
D
Q
A
S
W
E
S
Rhesus Macaque
Macaca mulatta
XP_001107319
1912
217912
Y649
I
K
W
R
D
L
P
Y
D
Q
A
S
W
E
S
Dog
Lupus familis
XP_534909
1912
217966
Y649
I
K
W
R
D
L
P
Y
D
Q
A
S
W
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
Y642
I
K
W
R
D
L
P
Y
D
Q
A
S
W
E
S
Rat
Rattus norvegicus
Q9JIX5
2581
290674
F719
F
H
E
D
E
E
P
F
N
P
D
Y
V
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
Y836
V
K
Y
K
N
F
S
Y
L
H
C
Q
W
A
S
Frog
Xenopus laevis
NP_001080504
1893
214670
Y640
I
K
W
R
D
L
A
Y
D
Q
A
S
W
E
A
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
F755
F
Q
E
D
E
E
P
F
N
P
D
Y
V
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
Y639
V
K
W
R
E
L
P
Y
D
K
S
T
W
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
T587
G
P
K
E
D
E
V
T
S
R
R
K
K
R
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
H323
F
E
E
N
L
I
P
H
L
V
I
A
P
L
S
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
K407
A
D
E
M
G
L
G
K
T
V
Q
T
V
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.7
99.3
N.A.
98.1
22.8
N.A.
N.A.
22.6
84.5
23.1
N.A.
55.7
N.A.
43.2
N.A.
Protein Similarity:
100
98.9
99.7
99.5
N.A.
98.6
36.9
N.A.
N.A.
35
90.5
38.4
N.A.
69.5
N.A.
59.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
26.6
86.6
13.3
N.A.
60
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
53.3
93.3
40
N.A.
93.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.6
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.4
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
47
8
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
16
54
0
0
0
54
0
16
0
0
0
0
% D
% Glu:
0
8
31
8
24
24
0
0
0
0
0
0
0
70
16
% E
% Phe:
24
0
0
0
0
8
0
16
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
47
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
62
8
8
0
0
0
8
0
8
0
8
8
0
0
% K
% Leu:
0
0
0
0
8
62
0
0
16
0
0
0
0
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
16
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
70
0
0
16
0
0
8
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
47
8
8
0
0
0
% Q
% Arg:
0
0
0
54
0
0
0
0
0
8
8
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
8
0
8
0
8
47
0
0
54
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
0
16
0
0
0
% T
% Val:
16
0
0
0
0
0
8
0
0
16
0
0
24
0
16
% V
% Trp:
0
0
54
0
0
0
0
0
0
0
0
0
62
0
0
% W
% Tyr:
0
0
8
0
0
0
0
62
0
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _